Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The strategy exploits the selectivity of the enzyme legumain for the specific release of amine-containing natural products.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648515 | PMC |
| http://dx.doi.org/10.1039/d2cc04905h | DOI Listing |
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