Objective: The physiological interaction between the left ventricle (LV) and the arterial system, defined as ventricular-arterial coupling (VAC), facilitates the optimal volume of cardiac work and cardiovascular performance. The aim of this study was to evaluate the benefit of PWV/GLS ratio associated with other vascular and cardiac performance parameters in hypertensive patients compared to age-matched healthy controls.
Patients And Methods: We calculated the ratio of pulse wave velocity (PWV), as a marker of arterial stiffness, to global longitudinal strain (GLS), as a marker of left ventricular function in 135 patients divided in 3 groups, as follows: group 1 (HT + CAD) enrolled 54 hypertensive patients with coronary artery disease, group 2 (HT) enrolled 43 hypertensive patients and group 3 (CON) represented the control group consisting of 38 age-matched healthy subjects.
Results: GLS values were significantly reduced in HT+CAD (-17.50±7.2) vs. HT (-17.95±5.3) vs. control (-20.13±4.6) (p-value <0.001). PWV values were higher in HT+CAD (9.90±3.1) and HT (9.70±2.5) vs. control (7.85±3.2) (p-value <0.001). VA coupling measured by the PWV/GLS ratio showed significantly lower values in HT+CAD and HT vs. control (p-value <0.001). The ROC curve identified a threshold of -0.054 of the PWV/GLS ratio to detect altered ventricular-arterial coupling AUROC = 0.836, 95% CI [0.762; 0.909].
Conclusions: This study demonstrated that assessment of the PWV/GLS ratio represents a useful tool to detect altered ventricular-arterial coupling in hypertensive patients. The perspectives of future use could include monitoring of earlier development of multiple organ damage in hypertensive patients and the efficacy of the different hypertensive medications. Extensive prospective studies are needed to confirm this hypothesis.
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http://dx.doi.org/10.26355/eurrev_202210_29886 | DOI Listing |
Ann Plast Surg
January 2025
From the Division of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT.
Background: Direct-to-implant (DTI) breast reconstruction offers immediate aesthetic and psychological benefits, but the role of acellular dermal matrix (ADM) remains debated. Using a multi-institutional database, this study evaluates and compares outcomes between ADM-assisted and non-ADM DTI procedures.
Methods: The American College of Surgeons National Surgical Quality Improvement Program database from 2008 to 2022 was queried to identify female patients who underwent DTI breast reconstruction for oncological purposes.
Objective: Aim: To investigate the effects of exercise training on heart rate and blood pressure in soccer players of different skill levels.
Patients And Methods: Materials and Methods: 693 soccer players with different sports qualifications were studied. Heart rate (HR) and blood pressure (BP) were measured at rest at the beginning of the preparatory phase of the training cycle.
Wiad Lek
January 2025
DEPARTMENT OF CLINICAL PHARMACY AND THERAPEUTICS, FACULTY OF PHARMACY, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: This research aims to comprehensively assess the prescribing practices of anti-hypertensive medications in a sample of Iraqi patients with diabetes. Specifically, exploring medication types and classes, adherence to clinical guidelines for managing hypertension in the context of diabetes, and factors influencing prescribing decisions.
Patients And Methods: Materials and Methods: This descriptive cross-sectional retrospective study investigates medication usage in an outpatient clinic in Najaf, Iraq, utilizing systematic sampling.
Eur Heart J Cardiovasc Imaging
January 2025
Heart Institute. Department of Cardiology. Cardiovascular Imaging Unit. Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Aims: How the underlying etiology and pathophysiology of left ventricular (LV) hypertrophy affects LA remodeling and function remains unexplored. The present study aims to investigate the influence of various hypertrophic phenotypes on LA remodeling and function.
Methods And Results: Patients with LV hypertrophy who underwent cardiac magnetic resonance (CMR) were compared to a control group.
PLoS One
January 2025
Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Background: Medication adherence plays a crucial role in effectively managing hypertension, a significant public health concern, especially in regions like Central Vietnam. This study aimed to assess medication adherence levels among hypertensive patients in primary care settings and explore the factors influencing adherence within this specific population.
Methods: We conducted a cross-sectional study to evaluate medication adherence and its determinants among individuals with hypertension in Central Vietnam.
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