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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9574542PMC
http://dx.doi.org/10.1016/j.jdcr.2022.09.004DOI Listing

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Article Synopsis
  • Gastric nodules, commonly found in endoscopic procedures, can occasionally be xanthomas, rare lipid-filled lesions, as illustrated in a case involving a 50-year-old male patient.
  • The patient presented with symptoms related to gastroesophageal reflux disease (GERD), leading to an esophagogastroduodenoscopy (EGD) that revealed mild gastritis and xanthelasma.
  • Although xanthomas in the gastrointestinal tract are rare and typically benign, they can resemble malignancies, necessitating further investigation and management.
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Article Synopsis
  • Xanthomas are benign, yellow, soft skin lesions made up of fat-laden immune cells, often indicating underlying lipid issues in the body.
  • A 13-year-old girl had large, painless nodules on her elbows and knees for five years, and tests revealed a family history of similar lesions with abnormal lipid levels.
  • The case emphasizes the need for early diagnosis of xanthomas to prevent serious health problems like heart disease and strokes in young patients.
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Perifollicular Xanthoma Occurring in Patients after Erlotinib Treatment.

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May 2022

Department of Dermatology, College of Medicine, Chungbuk National University, Chungdae-ro 1, Seowon-Gu, Cheongju, Chungbuk, 28644, South Korea.

Erlotinib (Tarceva) is a drug used for the treatment of non-small cell lung cancer in patients with epidermal growth factor receptor (EGFR) mutations. Since EGFR is expressed in the skin, EGFR inhibitors commonly develop cutaneous side effects such as acneiform eruption, paronychia, telangiectasias, and abnormal eyelash growth. A 56-year-old man and a 46-year-old man visited the dermatology clinic complaining of yellowish papuloplaques and acneiform eruption on the face.

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