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Epidemiology of Tomato Brown Rugose Fruit Virus (ToBRFV) in Commercial Greenhouses.
Plant Dis
November 2024
Institut national de la recherche scientifique, Centre Armand Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, Quebec, Canada, H7V 1B7;
The tomato brown rugose fruit virus (ToBRFV) poses a considerable threat to tomato production worldwide. Substantial experimental evidence supports the role of infected seeds as a contamination route, but the epidemiologic portrait of the virus has received less attention. This study reports the first survey of ToBRFV prevalence in commercial greenhouses.
View Article and Find Full Text PDFTranscriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states.
Nat Aging
December 2024
Genetics, Genomics and Development Graduate Program, Cornell University, Ithaca, NY, USA.
In aging, skeletal muscle regeneration declines due to alterations in both myogenic and non-myogenic cells and their interactions. This regenerative dysfunction is not understood comprehensively or with high spatiotemporal resolution. We collected an integrated atlas of 273,923 single-cell transcriptomes and high-resolution spatial transcriptomic maps from muscles of young, old and geriatric mice (~5, 20 and 26 months old) at multiple time points following myotoxin injury.
View Article and Find Full Text PDFThe genomic portrait of the Picene culture provides new insights into the Italic Iron Age and the legacy of the Roman Empire in Central Italy.
Genome Biol
November 2024
Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.
Background: The Italic Iron Age is characterized by the presence of various ethnic groups partially examined from a genomic perspective. To explore the evolution of Iron Age Italic populations and the genetic impact of Romanization, we focus on the Picenes, one of the most fascinating pre-Roman civilizations, who flourished on the Middle Adriatic side of Central Italy between the 9 and the 3 century BCE, until the Roman colonization.
Results: More than 50 samples are reported, spanning more than 1000 years of history from the Iron Age to Late Antiquity.
Morphological and molecular mechanisms of floral nectary development in Chinese Jujube.
BMC Plant Biol
November 2024
College of Forestry, Northwest A&F University, Yangling, Shaanxi, 712100, China.
Background: Chinese jujube (Ziziphus jujuba Mill.), also called Chinese date, is one of the oldest and widely cultivated fruit trees with great economic values, which, at least, can be attributed to the melliferous flower with highly developed nectary that can secret huge amount of nectar in a rather tiny floral size. However, the morphological nature, metabolic products, developmental process, as well as molecular and regulatory mechanisms of jujube nectary remain largely unknown.
View Article and Find Full Text PDFA unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer.
bioRxiv
September 2024
Department of Genetics, Harvard Medical School, Boston, MA, USA.
Article Synopsis
- The study investigates whether primary tumor cells can metastasize randomly or require specialized traits by examining 26 colorectal cancer patients with peritoneal metastases.
- Using a detailed sampling method, the research finds that peritoneal metastases are more heterogeneous than liver metastases and influenced by factors like chemotherapy.
- The origins of peritoneal metastases are often at the deep-invading edge of primary tumors and generally do not share a common subclonal origin with distant metastases, indicating different selective pressures impacting cancer cells during metastasis.
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