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http://dx.doi.org/10.1038/s41398-022-02219-y | DOI Listing |
Ann Transl Med
December 2024
[This corrects the article DOI: 10.21037/atm-22-2043.].
View Article and Find Full Text PDFHeliyon
July 2024
The Design School, Taylor's University, Subang Jaya, Selangor, Malaysia.
Road traffic injuries are one of the main causes of death among children. In recent years, the incidence and casualty rates of traffic accidents have increased year by year, which is a major challenge faced by safety organizations and governments in various countries, especially in developing countries. Among them, correct understanding of road traffic signs is a factor in reducing accidents.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Two-photon phosphorescence lifetime microscopy has been a key tool for studying cerebral oxygenation in mice. However, the accuracy of the partial pressure of oxygen (pO) measurements is affected by out-of-focus signal. In this work, we applied reconfigurable differential aberration imaging to characterize and correct for out-of-focus signal contamination in intravascular pO imaging.
View Article and Find Full Text PDFNarra J
December 2024
Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Alzheimer's disease (AD) is the most frequent form of dementia and represents an increasing global burden, particularly in countries like Indonesia, where the population has begun to age significantly. Current medications, including cholinesterase inhibitors and NMDA receptor antagonists, have modest effects on clinical symptoms in the early to middle stages, but there is no curative treatment available so far despite progress. Activating or repressing epigenetic modifications, including DNA methylation, histone modification and microRNA regulation, appears to play an important role in AD development.
View Article and Find Full Text PDFNature
January 2025
Department of Brain and Cognitive Sciences and McGovern Institute, MIT, Cambridge, MA, USA.
Hippocampal circuits in the brain enable two distinct cognitive functions: the construction of spatial maps for navigation, and the storage of sequential episodic memories. Although there have been advances in modelling spatial representations in the hippocampus, we lack good models of its role in episodic memory. Here we present a neocortical-entorhinal-hippocampal network model that implements a high-capacity general associative memory, spatial memory and episodic memory.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!