AI Article Synopsis

  • Graves' dermopathy is a skin condition related to Graves' disease, highlighted by the buildup of glycosaminoglycans in the skin's deeper layers.
  • Most cases of pretibial myxedema resolve on their own, but some can cause significant damage.
  • Conventional treatment includes topical steroids, though intralesional steroids, like triamcinolone acetate, have shown effective results in some cases.

Article Abstract

Graves' dermopathy is one of the extra-thyroidal manifestations of Graves' disease (GD) and is characterized by the accumulation of glycosaminoglycans in the reticular dermis. In the majority of cases, pretibial myxedema is self-limiting but, in some cases, it can lead to structural and functional damage. Topical steroids with occlusive dressing remain the conventional treatment, but intralesional steroids have shown promising results. We hereby present a case of pretibial myxedema treated successfully with intralesional triamcinolone acetate.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573773PMC
http://dx.doi.org/10.7759/cureus.29234DOI Listing

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