Analysis of reaction between vitamin B and bovine serum albumin based on a terahertz metamaterial sensor.

A four-peak terahertz metamaterial sensor was used to detect the reaction between different concentrations of vitamin () and bovine serum albumin (BSA), which achieves a concentration range (0.015-0.125 mg/µl) of and a maximum binding concentration (0.05 mg/µl) of and 0.0875 mg/µl BSA. To understand the combination of and BSA, the reactants between VB (, , and ) with the same concentration (0.05 mg/µl) and a BSA solution with a concentration of 0.0875 mg/µl were carried on the surface of the sensor. Experimental results show that the reactants cause the four resonance peaks of the sensor to produce the coincident redshift, which is the same as the order of their binding coefficients determined by the fluorescence method. The experimental process indicates that it is feasible to use terahertz metamaterials to detect the reaction process of organic matter.