In the present work, the inclusion complexes between curcumin (CC) and β-cyclodextrin (β-CD) were obtained through co-precipitation at different times of magnetic stirring and simple mixing. The stoichiometric ratio between CC and β-CD was ascertained to be 1:2. The samples prepared by co-precipitation (24 h magnetic stirring and 24 h cold static precipitation) and by simple mixing, showed the best performance in terms of powder recovery (72 and 97%, respectively), encapsulation efficiency (72 and 95%, respectively) and tinting power, while no significant differences were revealed in terms of loading capacity (about 14%). Using either inclusion method, the complexation of CC into β-CD make the colorant 20-fold more water soluble than pure CC. The pigment stability was also enhanced under different storage conditions (high temperature and light exposure), either when applied in liquid or gel state. However, after 30 days under natural light exposure, an appreciable colour change from yellow to orange was revealed to an extent probably perceptible by an inexperienced observer.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/19440049.2022.2135764 | DOI Listing |
Int J Nanomedicine
January 2025
Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Purpose: Dimethyl fumarate (DMF), the first-line oral therapy for relapsing-remitting multiple sclerosis, is rapidly metabolized into monomethyl fumarate. The DMF oral administration provokes gastrointestinal discomfort causing treatment withdrawal. The present study aimed to develop an innovative formulation for DMF nasal administration.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Mechanical and Manufacturing Department, Mondragon University, 20500 Mondragon, Spain.
This study investigates fixed and moving mesh methodologies for modeling liquid metal-free surface deformation during the induction melting process. The numerical method employs robust coupling of magnetic fields with the hydrodynamics of the turbulent stirring of liquid metal. Free surface tracking is implemented using the fixed mesh level set (LS) and the moving mesh arbitrary Lagrangian-Eulerian (ALE) formulation.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Institute of Physical Metallurgy, Metal Forming & Nanotechnology, University of Miskolc, 3515 Miskolc, Hungary.
The microstructure of hypereutectic Al-Si alloys is crucial in determining their mechanical properties and overall performance in engineering applications. This paper investigates the effect of a rotating magnetic field (RMF) and eutectic front velocity on the microstructure of hypereutectic Al-18 wt.% Si alloy.
View Article and Find Full Text PDFRapid Commun Mass Spectrom
April 2025
Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, and Cancer Center, School of Medicine, Tongji University, Shanghai, China.
Rationale: The performance of the capillary column directly impacts the separation efficiency of complex sample in liquid chromatography-mass spectrometry-based proteomics studies. The hydraulic packing system offers an effective solution by reducing packing time and expediting the preparation process of column preparation. However, its operational complexity and strict parameter regulation requirements hinder efficient application.
View Article and Find Full Text PDFBiosensors (Basel)
December 2024
School of Engineering, University of Guelph, Guelph, ON N1G 2W1, Canada.
Receptor-based biosensors often suffer from slow analyte diffusion, leading to extended assay times. Moreover, existing methods to enhance diffusion can be complex and costly. In response to this challenge, we presented a rapid and cost-effective technique for fabricating concave magnetic-responsive hydrogel discs (CMDs) by straightforward pipetting directly onto microscope glass slides.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!