Biological Activity and Chemical Composition of Guill. and Perr-A Systematic Review.

Adv Pharmacol Pharm Sci

Biology Education Department, Faculty of Education, Tishk International University, Erbil, Kurdistan Region, Iraq.

Published: October 2022

AI Article Synopsis

  • Natural products have historically been important for treating diseases, with traditional practices using them for conditions like diabetes, malaria, and cancer.
  • The study emphasizes the need for consistent research methodologies to make reliable comparisons across various studies.
  • Findings indicate that the leaves and stem bark possess beneficial properties, but excessive consumption can be harmful, highlighting a need for further clinical trials to ensure safety and efficacy.

Article Abstract

Historically, natural products have been the principal source of medications for the treatment of human diseases. Traditional medical practitioners employ as a treatment for diabetes, malaria, wounds, inflammation, and even cancer. This study emphasizes the importance of harmonizing research so that results from various sources may be directly compared to reach a scientific conclusion. We searched Google Scholar, Science Direct, Google.com, Wiley, PubMed, Hindawi, and Springer for research papers on . This analysis excludes untrustworthy online data, thesis papers, and review publications on . The leaves and stem bark were shown to have high antioxidant, anti-inflammatory, antibacterial, antidiabetic, and anticancer properties. The study also discovered that too much consumption is harmful. Polyphenols and flavonoids were the most commonly reported compounds. However, human safety and efficacy are yet to be fully evaluated, and further well-designed clinical trials are needed to confirm preclinical findings. The leaves and stem bark extracts and isolated compound mechanism of action should be investigated. It is necessary to set a standard dose and ensure its safety.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569227PMC
http://dx.doi.org/10.1155/2022/7219401DOI Listing

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