Biotechnological impacts of : a promising cell factory for industrially relevant biomolecules.

Biotechnol Genet Eng Rev

Laboratory of Molecular Bacteriology, Department of Microbiology, University of Calcutta, Kolkata, India.

Published: October 2023

Extremophiles are the most fascinating life forms for their special adaptations and ability to offer unique extremozymes or bioactive molecules. Halophiles, the natural inhabitants of hypersaline environments, are one among them. are the common genus of halophilic bacteria. To support growth in unusual environments, produces various hydrolytic enzymes, compatible solutes, biopolymers like extracellular polysaccharides (EPS) and polyhydroxy alkaloates (PHA), antibiotics, biosurfactants, pigments, etc. Many of such molecules are being produced in large-scale bioreactors for commercial use. However, the prospect of the remaining bioactive molecules with industrial relevance is far from their application. Furthermore, the genetic engineering of the respective gene clusters could open up a new path to bio-prospect these molecules by overproducing their products through heterologous expression. The present survey on highlights their ecological diversity, application potential of the their various industrially relevant biomolecules and impact of these biomolecules on respective fields.

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Source
http://dx.doi.org/10.1080/02648725.2022.2131961DOI Listing

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