Feasibility, Acceptability, and Preliminary Impact of Full-Body Interaction on Computerized Cognitive Training Based on Instrumental Activities of Daily Living: A Pilot Randomized Controlled Trial with Chronic Psychiatric Inpatients.

To conduct a pilot randomized control trial to assess the feasibility and acceptability of full-body interaction cognitive training (FBI-CT) inspired by instrumental activities of daily living in chronic psychiatric inpatients and to explore its preliminary impact on cognitive and noncognitive outcomes. Twenty psychiatric inpatients met the inclusion criteria and were randomly allocated to the FBI-CT group ( = 10) or the tablet-based CT group (T-CT) ( = 10). Neuropsychological assessments were performed at baseline, postintervention, and 3-month follow-up. Both groups presented high completion rates at postintervention and follow-up. Participants reported high satisfaction following the interventions, with the FBI-CT group exhibiting slightly higher satisfaction. A within-group analysis showed significant improvements in the FBI-CT group for processing speed and sustained attention for short periods ( = 0.012), verbal memory ( = 0.008), semantic fluency ( = 0.027), depressive symptoms ( = 0.008), and quality of life ( = 0.008) at postintervention. At 3-month follow-up, this group maintained verbal memory improvements ( = 0.047) and depressive symptoms amelioration ( = 0.026). The T-CT group revealed significant improvements in sustained attention for long periods ( = 0.020), verbal memory ( = 0.014), and executive functions ( = 0.047) postintervention. A between-group analysis demonstrated that the FBI-CT group exhibited greater improvements in depressive symptoms ( = 0.042). Overall, we found support for the feasibility and acceptability of both training approaches. Our findings show promise regarding the preliminary impact of the FBI-CT intervention, but due to study limitations such as the small sample size, we cannot conclude that FBI-CT is a more effective approach than T-CT for enhancing cognitive and noncognitive outcomes of chronic psychiatric inpatients. Clinical trials (number: NCT05100849).