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Alpha Guy? No, Alpha Gal-Important to Remember in Patients with IBD in Endemic Areas.
Dig Dis Sci
November 2024
University of North Carolina at Chapel Hill, Chapel Hill, USA.
Extinction training suppresses activity of fear memory ensembles across the hippocampus and alters transcriptomes of fear-encoding cells.
Neuropsychopharmacology
November 2024
Department of Neuroscience, The University of Texas at Austin, Austin, TX, USA.
Contextual fear conditioning has been shown to activate a set of "fear ensemble" cells in the hippocampal dentate gyrus (DG) whose reactivation is necessary and sufficient for expression of contextual fear. We previously demonstrated that extinction learning suppresses reactivation of these fear ensemble cells and activates a competing set of DG cells-the "extinction ensemble." Here, we tested whether extinction was sufficient to suppress reactivation in other regions and used single nucleus RNA sequencing (snRNA-seq) of cells in the dorsal dentate gyrus to examine how extinction affects the transcriptomic activity of fear ensemble and fear recall-activated cells.
View Article and Find Full Text PDFBodily contrast experiences in cultivating character for care.
Nurs Ethics
February 2024
Faculty of Theology and Religious Studies, KU Leuven, Leuven, Belgium.
Since 2008, in Flanders, we organize immersion sessions in a simulated context with the aim of stimulating student nurses and health professionals to learn virtuous caring. In this contribution, we first outline the purpose of this experiential learning: the cultivation of moral character. We come to the core of what we mean by moral character for care.
View Article and Find Full Text PDFNo structural brain alterations in new daily persistent headache - a cross sectional VBM/SBM study.
Cephalalgia
April 2022
Department of Neurology, Westgerman Headache Center, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.
Objective: To identify grey matter alterations in patients suffering new daily persistent headache to enrich the pathophysiological concept of this rare headache disorder characterised by a distinct, clearly remembered onset and its instant chronification.
Method: Magnetic resonance-based voxel-based and surface-based morphometry was used to investigate 23 patients suffering from new daily persistent headache and 23 age- and gender-matched healthy controls with 1.5 Tesla MRI.
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