The low (90 K) and room (298 K) temperature crystal structures of topiramate azido-sulfate [systematic name 2,3:4,5-bis--(1-methyl-ethyl-idene)-β-d-fructo-pyran-ose azido-sulfate], CHNOS, an inter-mediate in the synthesis of the anti-convulsant drug topiramate, are described. Topiramate azido-sulfate () finds use as a reference impurity standard for topiramate. A modified synthesis and some spectroscopic details are also presented.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535817 | PMC |
| http://dx.doi.org/10.1107/S2056989022008799 | DOI Listing |
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