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Desmoplastic small round cell tumor involving the uterine cervix: The first reported case in the literature, and brief review of gynecologic presentations. | LitMetric

AI Article Synopsis

  • Desmoplastic small round cell tumors are very rare and primarily affect male patients, but this case is notable because it originated in the uterine cervix, a first of its kind.
  • A 54-year-old woman had a large tumor in her cervix, and after initial treatment involving chemotherapy and surgery, she experienced a recurrence that was successfully managed with radiation therapy.
  • The case emphasizes the importance of a multidisciplinary approach to treatment, as there is currently no established standard for managing these tumors, providing valuable insights for future patients.

Article Abstract

Background: Desmoplastic small round cell tumors are exceedingly rare, usually involve abdominal organs and predominantly affect male patients. We describe the first reported case arising from the uterine cervix and provide a summary of 20 previously reported cases involving gynecologic organs.

Case: A 54 year-old was diagnosed with a rapidly growing 13 cm desmoplastic small round cell tumor of the cervix. She was treated through a multimodal approach involving neoadjuvant chemotherapy and surgery. She subsequently recurred, and this was successfully treated with radiation therapy. She is well and without evidence of disease 22 months after initial diagnosis.

Conclusion: We report successful treatment through multidisciplinary and multimodal management. This can guide management of future patients as no gold-standard treatment has yet been described.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556919PMC
http://dx.doi.org/10.1016/j.gore.2022.101079DOI Listing

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