[This corrects the article DOI: 10.1021/acsomega.2c04316.].
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http://dx.doi.org/10.1021/acsomega.2c05858 | DOI Listing |
Sci Rep
December 2024
Department of Mechanics, Xi'an University of Science and Technology, Xi'an, 710054, China.
Under confining pressure, rocks transition from brittle failure to plastic failure, and residual strength exists after complete failure. However, in the process of establishing rock damage constitutive models, the strength criteria used usually do not consider residual stress. In cold region engineering, the freeze-thaw effect caused by temperature changes should be considered in the constitutive model, and strength criteria should also be introduced.
View Article and Find Full Text PDFSci Rep
December 2024
School of Mechanics and Engineering, Liaoning Technical University, Fuxin, 123000, Liaoning, China.
This paper first conducted a shale injection CO seepage experiment based on an improved single-vessel pressure pulse attenuation method. The experimental results reveal that the evolution pattern of shale permeability with respect to pore pressure can be divided into before and after phase change. The overall trend is that it first decreases and then increases, which is not a simple exponential form.
View Article and Find Full Text PDFUntil the beginning of the century, bleeding management was similar in elective surgeries or exsanguination scenarios: clotting tests were used to guide blood product orders and, while awaiting these results, an aggressive resuscitation with crystalloids was recommended. The high mortality rate in severe hemorrhages managed with this strategy endorsed the need for a special resuscitation plan. As a result, modifications were recommended to develop a new clinical approach to these patients, called "Damage Control Resuscitation".
View Article and Find Full Text PDFJ Fungi (Basel)
November 2024
Key Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
is a dimorphic fungus that specifically infects , causing stem swelling and the formation of an edible fleshy stem known as jiaobai. The pathogenicity of is closely associated with the development of jiaobai and phenotypic differentiation. Msb2 acts as a key upstream sensor in the MAPK (mitogen-activated protein kinase) signaling pathway, playing critical roles in fungal hyphal growth, osmotic regulation, maintenance of cell wall integrity, temperature adaptation, and pathogenicity.
View Article and Find Full Text PDFJ Pharm Sci
December 2024
SSPC Centre for Pharmaceutical Research, School of Pharmacy, University College Cork, Cork, T12 YT20, Ireland. Electronic address:
With the increasing development of oral peptide dosage forms, a comprehensive understanding of factors affecting peptide drug stability in the solid-state is critical. This study used human insulin, as a model peptide, to examine the individual and interactive effects of temperature and humidity on its solid-state stability. Insulin was stored at temperature (25°C, 40°C, and 6 °C) and humidity (1%, 33% and 75%) over 6 months.
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