AI Article Synopsis
- Nesidioblastosis is a rare pancreatic condition characterized by the enlargement of beta cells that produce excessive insulin, leading to fasting hypoglycemia.
- A 53-year-old woman diagnosed with the condition underwent various imaging tests which initially showed no abnormalities, but selective arterial calcium stimulation confirmed increased insulin production from some pancreatic arteries.
- The diagnosis was confirmed through histopathology after surgery, and post-operation, the patient achieved normal glucose levels and resolved hypoglycemia, indicating a limited extent of the disease within the pancreas.
Article Abstract
Nesidioblastosis is a rare pancreatic disorder involving enlarged beta cells throughout the pancreas, causing elevated insulin production. We present the case of a 53-year-old woman with the initial symptom of fasting hypoglycemia. No pancreatic lesions were indicated on computed tomography and magnetic resonance imaging scans, and an octreotide scan was negative for insulinoma. Selective arterial calcium stimulation (SACST) showed increased insulin production from the stimulation of 3 out of 5 arteries. The SACST results suggested a diagnosis of nesidioblastosis, which was confirmed by histopathology after a subtotal distal pancreatectomy. The patient has normal glucose tolerance after surgery with no further problems of hypoglycemia, indicating that this is a rare case of nesidioblastosis extending only partially through the pancreas.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568342 | PMC |
| http://dx.doi.org/10.1155/2022/2802975 | DOI Listing |
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