Novel Molecular Barcoding for Rapid Pathogen Detection in Infectious Keratitis.

Ophthalmol Sci

Department of Ophthalmology, Massachusetts Eye and Ear, and Infectious Disease Institute, Harvard Medical School, Boston, Massachusetts.

Published: December 2021

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559883PMC
http://dx.doi.org/10.1016/j.xops.2021.100066DOI Listing

Publication Analysis

Top Keywords

novel molecular
4
molecular barcoding
4
barcoding rapid
4
rapid pathogen
4
pathogen detection
4
detection infectious
4
infectious keratitis
4
novel
1
barcoding
1
rapid
1

Similar Publications

Crystalline Covalent Triazine Frameworks and 2D Triazine Polymers: Synthesis and Applications.

Acc Chem Res

January 2025

School of Engineering, Westlake University, Hangzhou 310024, Zhejiang Province, China.

ConspectusCovalent triazine frameworks (CTFs) are a novel class of nitrogen-rich conjugated porous organic materials constructed by robust and functional triazine linkages, which possess unique structures and excellent physicochemical properties. They have demonstrated broad application prospects in gas/molecular adsorption and separation, catalysis, energy conversion and storage, etc. In particular, crystalline CTFs with well-defined periodic molecular network structures and regular pore channels can maximize the utilization of the features of CTFs and promote a deep understanding of the structure-property relationship.

View Article and Find Full Text PDF

Colorectal cancer (CRC) is one of the most prevalent and deadly malignancies worldwide. Recently, ferroptosis, a novel form of regulated cell death characterized by iron dependency and lipid peroxidation, has garnered significant attention from researchers. The mechanisms underlying ferroptosis, including intracellular iron levels, lipid peroxidation, and antioxidant system regulation, offer new insights into cancer treatment strategies.

View Article and Find Full Text PDF

Squamate reptiles may have compensated for the lack of γδTCR with a duplication of the TRB locus.

Front Immunol

January 2025

Center for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM, United States.

Squamate reptiles are amongst the most successful terrestrial vertebrate lineages, with over 10,000 species across a broad range of ecosystems. Despite their success, squamates are also amongst the least studied lineages immunologically. Recently, a universal lack of γδ T cells in squamates due to deletions of the genes encoding the T cell receptor (TCR) γ and δ chains was discovered.

View Article and Find Full Text PDF

Background: Adenocarcinoma of the esophagogastric junction (AEGJ) is a highly aggressive tumor that frequently metastasizes to the liver. Understanding the cellular and molecular mechanisms that drive this process is essential for developing effective therapies.

Methods: We employed single-cell RNA sequencing to analyze the tumor heterogeneity and microenvironmental landscape in patients with AEGJ liver metastases.

View Article and Find Full Text PDF

Background: Colon adenocarcinoma (COAD) is a malignancy with a high mortality rate and complex biological characteristics and heterogeneity, which poses challenges for clinical treatment. Anoikis is a type of programmed cell death that occurs when cells lose their attachment to the extracellular matrix (ECM), and it plays a crucial role in tumor metastasis. However, the specific biological link between anoikis and COAD, as well as its mechanisms in tumor progression, remains unclear, making it a potential new direction for therapeutic strategy research.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!