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Salvage Stereotactic Radiotherapy for Nodal Oligo-Recurrent Prostate Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Clin Genitourin Cancer
December 2024
Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan. Electronic address:
Background: Prostate cancer has a high frequency of relapse, and the relapse is usually associated with a nodal recurrence pattern spreading predominantly to fewer pelvic or extra-pelvic lymph nodes. This meta-analysis sought to determine the safety and survival outcomes of salvage body stereotactic radiotherapy (SBRT) in oligo-recurrent nodal prostate cancer patients.
Methods: We searched the Cochrane Central Register of Controlled Trials, PubMed, ClinicalTrials.
Prostate-specific membrane antigen-radioguided surgery salvage lymph node dissection: experience with fifty oligorecurrent prostate cancer patients.
World J Urol
August 2024
Department of Nuclear Medicine, University of Regensburg, 93053, Regensburg, Germany.
Article Synopsis
- The study focuses on evaluating the effectiveness of PSMA-targeted radioguided surgery (PSMA-RGS) for treating patients with oligometastatic recurrence of prostate cancer, highlighting new regional treatment options.
- Between 2018 and 2022, 50 out of 53 patients who underwent PSMA-RGS after initial radical prostatectomy were analyzed, with successful removal of pathologically positive lesions in all cases.
- Although PSMA-RGS showed promise, only 42% of patients remained free from biochemical recurrence during follow-up, indicating the need for further research to better select candidates for this treatment.
The relationship between the treatment course and prognosis of oligometastasis after esophageal squamous cell carcinoma resection.
Surg Today
August 2024
Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Purpose: The concept of oligometastasis, which represents limited metastatic disease, has recently gained interest, accompanied by a more detailed classification. This study aims to investigate the relationship between the treatment course and prognosis in patients with a recurrence of esophageal squamous cell carcinoma (ESCC) after curative esophagectomy.
Methods: 126 patients with ESCC recurrence after curative resection were enrolled in this study.
Is oligometastatic disease an applicable and useful concept in haematologic malignancies? A narrative review of radiation therapy standards, modern techniques, and innovations.
Cancer Radiother
February 2024
Department of Radiation Oncology, centre Sein Henri-Mondor, CHU Henri-Mondor, AP-HP, university Paris Est Créteil (Upec), Créteil, France; Institut Mondor de recherche biomédicale (IMRB), Inserm U955, i-Biot, Créteil, France.
Purpose: Haematologic malignancies are particular in that they can generally be cured, even when distant metastases are present at diagnosis, unlike solid malignancies. Systemic treatments, including chemotherapy, targeted therapies, and immunotherapy, are the standard of care with excellent results. The considerable progress made in the management of these diseases in the last 20years has redefined the role of radiation therapy as minor in many clinical situations.
View Article and Find Full Text PDFGenetic analysis of oligo-recurrence breast cancer: correlation with clinical outcomes.
BMC Cancer
September 2023
Department of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Background: We aimed to identify the relationship between the genomic characteristics and clinical outcomes of oligo-metastatic breast cancer.
Methods: Oligo-metastatic breast cancer diagnosed by pathology from January 2001 and August 2019 were reviewed and we matched the poly-metastatic patients based on the clinicopathological features of patients included. Clinicopathological values and data of genomic alterations were collected.
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