Molecular Imaging for Estrogen Receptor-Positive Breast Cancer: Clinical Applications of Whole Body and Dedicated Breast Positron Emission Tomography.

Surg Oncol Clin N Am

Division of Surgical Oncology, Department of Surgery, University of California, San Francisco, 1825 4th Street, 3rd Floor, Box 1710, San Francisco, CA 94143, USA. Electronic address:

Published: October 2022

F-fluoroestradiol (F-FES) is a Food and Drug Administration-approved radiopharmaceutical used for molecular imaging of the estrogen receptor (ER). When combined with PET, F-FES may improve the diagnosis of ER-positive breast cancer in the metastatic setting and provide insights into tumor heterogeneity. In this article, we review data on the use of F-FES imaging for treatment selection, staging, imaging lobular breast cancer, and the novel breast specific imaging tool, dedicated breast PET.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277169PMC
http://dx.doi.org/10.1016/j.soc.2022.06.001DOI Listing

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