AI Article Synopsis
- Free wall rupture is a serious and often fatal complication that can occur after an acute myocardial infarction (heart attack), and the study aimed to identify factors linked to in-hospital mortality from this condition.
- A retrospective analysis of 111 patients with free wall rupture from 2005 to 2021 revealed that 87 of them died in the hospital, with specific factors like pericardiocentesis and pre-existing pericardial effusion being associated with lower mortality rates.
- Key findings indicated that timely medical intervention and the patient's history of heart issues significantly impact survival rates following free wall rupture after a heart attack.
Article Abstract
Background: Free wall rupture is a fatal and emergency complication of acute myocardial infarction. The factors associated with in-hospital mortality from free wall rupture remain unclear.
Objectives: To investigate the factors associated with in-hospital mortality from free wall rupture.
Methods: We performed a single-center, retrospective study. We enrolled 111 consecutive patients with free wall rupture following acute myocardial infarction who were admitted to Fuwai Hospital from January 2005 to May 2021. The primary endpoint was in-hospital death. Clinical characteristics, laboratory data, and treatment modalities associated with in-hospital mortality were analyzed.
Results: Eighty-seven of the 111 study participants died in hospital. Multivariate Cox regression analysis showed that pericardiocentesis (hazard ratio [HR] 0.296, 95% confidence interval [CI] 0.094-0.929, p = 0.037), pericardial effusion at admission (HR 0.083, 95% CI 0.025-0.269, p<0.001), time interval between acute myocardial infarction and free wall rupture (HR 0.670, 95% CI 0.598-0.753, p<0.001), and previous myocardial infarction (HR 0.046, 95% CI 0.010-0.208, p<0.001) were independently associated with in-hospital mortality.
Conclusions: Pericardiocentesis, pericardial effusion at admission, the acute myocardial infarction to free wall rupture time, and previous myocardial infarction are associated with a lower rate of in-hospital mortality from free wall rupture after acute myocardial infarction.
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| http://dx.doi.org/10.1016/j.hrtlng.2022.10.002 | DOI Listing |
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