AI Article Synopsis

  • Gold-coated tilted fiber Bragg gratings (TFBG) are advanced biosensors known for their high sensitivity to changes in the surrounding refractive index (RI).
  • Instead of just measuring insertion loss with single polarized light, the study employs the Jones formalism to enhance measurements by optimizing plasmonic excitation for both phase and amplitude detection.
  • The experimental results demonstrate a phase shift sensitivity of 45835/RIU while detecting HER2 proteins at a concentration of 1µg/ml, underscoring the method's improved precision for detecting small RI variations compared to traditional methods.

Article Abstract

Gold-coated tilted fiber Bragg gratings (TFBG) are refined plasmonic biosensors, highly sensitive to surrounding refractive index (RI) changes. Their interrogation usually relies on insertion loss measurements for single input polarized light, limiting the set of exploitable features. To overcome this limitation, we trigger the Jones formalism to retrieve the polarization enabling optimized plasmonic excitation for both phase and amplitude measurements. We present an experimental phase shift with a sensitivity as high as 45835/RIU and further assess this approach to HER2 proteins sensing at 1µg/ml. We compare this angular modality with the one relying on the insertion loss using a quality factor that takes the shift as well as the dispersion into account. This strengthens its relevance in terms of precision for ultra-small RI variations.

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Source
http://dx.doi.org/10.1364/OE.463140DOI Listing

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