Investigation on bioactive metabolites produced by an endophytic fungus from the arils of .

An endophytic fungus capable of producing active substances was isolated from the arils of . Seven compounds were separated from the ethyl acetate extract of fermentation broth and mycelium by chromatography, respectively identified as trichomerol (), bisorbicillinolide (), sohirnone A (), emodin (), stigmasterol (), ergosterol (), daidzein (). This study is the first to report of the isolation of the endophytic fungus from the arils of with complete assignments of -. Compound and exhibited significant antioxidant activity of diphenyl picryl hydrazinyl with IC 38.92 and 3.91 µg/mL, respectively. Compound , , and significantly inhibited the growth of with MIC 0.78; 0.39; 0.20 and 0.20 mg/mL, respectively. Current study indicated the presence of endophytic fungus in the arils of that could be responsible for the bioactive metabolite synthesis.