Background: Exercise efficiency and economy are key determinants of endurance exercise performance. In this cross-over intervention trial, we investigated the effect of adherence to a low carbohydrate, high fat (LCHF) diet versus a high carbohydrate (HC) diet on gross efficiency (GE) and (OC) during exercise, both after 2 days and after 14 days of adherence.
Methods: Fourteen recreational male athletes followed a two-week LCHF diet (<10 energy % carbohydrate) and a two-week HC diet (>50 energy % carbohydrate), in random order, with a wash-out period of three weeks in between. After 2 and 14 days on each diet, the athletes performed a 90-minutes submaximal exercise session on a bicycle ergometer. Indirect calorimetry measurements were done after 60 minutes of exercise to calculate GE and OC.
Results: GE was significantly lower on the LCHF diet compared to the HC diet, after 2 days (17.6±1.9 vs. 18.8±1.2%, P=0.011, for the LCHF and HC diet respectively), not after 14 days. OC was significantly higher on the LCHF diet compared to the HC diet, after 2 days (1191±138 vs. 1087±72 mL O
Conclusions: Although LCHF diets are popular strategies to increase fat oxidation during exercise, adherence to a LCHF diet was associated with a lower exercise efficiency and economy compared to a HC diet.
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http://dx.doi.org/10.23736/S0022-4707.22.14066-1 | DOI Listing |
Am J Physiol Cell Physiol
January 2025
Sansum Diabetes Research Institute, Santa Barbara, CA, USA.
Very-low-carbohydrate diets (LCHF; <50g/day) have been debated for their potential to lower pre-exercise muscle and liver glycogen stores and metabolic efficiency, risking premature fatigue. It is also hypothesized that carbohydrate ingestion during prolonged exercise delays fatigue by increasing carbohydrate oxidation, thereby sparing muscle glycogen. Leveraging a randomized crossover design, we evaluated performance during strenuous time-to-exhaustion (70%⩒O) tests in trained triathletes following 6-week high-carbohydrate (HCLF, 380g/day) or very-low-carbohydrate (LCHF, 40g/day) diets to determine (i) if adoption of the LCHF diet impairs time-to-exhaustion performance, (ii) whether carbohydrate ingestion (10g/hour) 6-12x lower than current CHO fuelling recommendations during low glycogen availability (>15-hour pre-exercise overnight fast and/or LCHF diet) improves time-to-exhaustion by preventing exercise-induced hypoglycemia (EIH; <3.
View Article and Find Full Text PDFClin Nutr
January 2025
Mohn Nutrition Research Laboratory, Department of Clinical Medicine, University of Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.
Front Nutr
November 2024
Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Background: Endothelial dysfunction (ED) is induced by insulin resistance, mediated by endoplasmic reticulum (ER) stress and disturbed autophagy. This study investigates the protective role of a low-carbohydrate, high-fat (LCHF) diet on ED, ER stress, and autophagy dysregulation in an experimental animal model of metabolic syndrome.
Methods: Forty male Sprague-Dawley rats were divided into four groups: a Control group (standard diet) and three Dexamethasone (DEX) treated groups.
Front Nutr
October 2024
Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.
Objective: In addition to recent discussions of low-carbohydrate, high-fat diets (LCHF) from a performance perspective, there is a paucity of knowledge regarding influence of the combined effect of an exercise and nutritional intervention, which varies in carbohydrate (CHO) intake and glycemic indices, on blood lipid levels in recreationally active men.
Methods: A total of 65 male runners (VO peak = 55 ± 8 mL·min·kg) completed a 10-week nutritional regimen (LOW-GI: ≥ 65% low GI CHO per day, = 24; HIGH-GI: ≥ 65% high GI CHO per day, = 20; LCHF: ≤ 50 g CHO daily, = 21) with a concurrent prescribed endurance training intervention. Fasting total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) were determined before and after the intervention.
Appetite
January 2025
Division of Physiological Sciences, Department of Human Biology, University of Cape Town, 7700, South Africa Health Through Physical Activity Lifestyle and Sport Research Centre, Sports Science Institute of South Africa, South Africa; International Federation of Sports Medicine (FIMS) Collaborative Centre of Sports Medicine, HPALS, University of Cape Town, 7700, South Africa; Research Center for Health Through Physical Activity, Lifestyle and Sport, Division of Physiology, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, 7700, South Africa.
South Africa faces a dual burden of non-communicable diseases (NCDs) and communicable diseases, exacerbated by the high consumption of processed foods. The Eat Better South Africa (EBSA) program implements community-based low-carbohydrate, high-fat (LCHF) interventions to address these issues. This study evaluated the impact of EBSA's 6-week program on the metabolic health and well-being of 32 women from underserved communities.
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