Many individuals fail to engage in sufficient physical activity (PA), despite its well-known health benefits. This paper examines Model Predictive Control (MPC) as a means to deliver optimized, personalized behavioral interventions to improve PA, as reflected by the number of steps walked per day. Using a health behavior fluid analogy model representing Social Cognitive Theory, a series of diverse strategies are evaluated in simulated scenarios that provide insights into the most effective means for implementing MPC in PA behavioral interventions. The interplay of measurement, information, and decision is explored, with the results illustrating MPC's potential to deliver feasible, personalized, and user-friendly behavioral interventions, even under circumstances involving limited measurements. Our analysis demonstrates the effectiveness of sensibly formulated constrained MPC controllers for optimizing PA interventions, which is a preliminary though essential step to experimental evaluation of constrained MPC control strategies under real-life conditions.
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http://dx.doi.org/10.23919/acc53348.2022.9867350 | DOI Listing |
J Neurol
January 2025
Parkinson's Disease Research Clinic, Macquarie University, 75 Talavera Road, Sydney, NSW, 2109, Australia.
Impulse Control Disorders (ICDs) are increasingly recognized as a significant non-motor complication in Parkinson's disease (PD), impacting patients and their caregivers. ICDs in PD are primarily associated with dopaminergic treatments, particularly dopamine agonists, though not all patients develop these disorders, indicating a role for genetic and other clinical factors. Studies over the past few years suggest that the mesocorticolimbic reward system, a core neural substrate for impulsivity, is a key contributor to ICDs in PD.
View Article and Find Full Text PDFActa Neurobiol Exp (Wars)
January 2025
Department of Physiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran; Bio Environmental Health Hazards Research Center, Jiroft University of Medical Sciences, Jiroft, Iran.
In recent years, growing evidence suggests that lipopolysaccharide (LPS), a bacterial endotoxin found in the outer membrane of gram‑negative bacteria, can influence cognitive functions, particularly memory formation and retrieval. However, the underlying mechanisms through which LPS exerts its effects on memory remain incompletely understood. This review used various electronic databases, including PubMed, Scopus, and Web of Science, to identify relevant studies published between 2000 and 2024.
View Article and Find Full Text PDFEat Disord
January 2025
Department of Psychology, Old Dominion University, Norfolk, Virginia, USA.
Young cisgender sexual minority women (e.g. lesbian, queer) in the U.
View Article and Find Full Text PDFMacromol Rapid Commun
January 2025
Qingdao Innovation and Development Center, Harbin Engineering University, Qingdao, 266000, China.
Hydrogels are flexible materials characterized by a 3D network structure, which possess high water content and adjustable physicochemical properties. They have found widespread applications in tissue engineering, electronic skin, drug delivery, flexible sensors, and photothermal therapy. However, hydrogel networks often exhibit swelling behavior in aqueous environments, which can result in structural degradation and a loss of gel performance.
View Article and Find Full Text PDFAppl Immunohistochem Mol Morphol
January 2025
Department of Pathology.
Histologic grade is a key predictor for pseudomyxoma peritonei (PMP) of appendiceal origin that is used to guide clinical management. However, some tumors demonstrate disease behavior that deviates from their histologic grade. A recent study suggested that TP53, GNAS, and RAS mutation analysis could stratify tumors into distinct molecular groups with different prognosis.
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