Five new furofurans lignans, Brasesquilignan A-E (), were isolated from the aqueous ethanol extract of Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and GCMS analysis. Furthermore, all compounds were evaluated for anti-proliferative activities against various human cancer cellsin vitro. Compounds and exhibited weak inhibitorypotency against five human cancer cells.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572557PMC
http://dx.doi.org/10.3390/molecules27196349DOI Listing

Publication Analysis

Top Keywords

brasesquilignan a-e
8
furofurans lignans
8
human cancer
8
a-e furofurans
4
lignans baker
4
baker furofurans
4
lignans brasesquilignan
4
a-e isolated
4
isolated aqueous
4
aqueous ethanol
4

Similar Publications

Brasesquilignan A-E, Five New Furofurans Lignans from Baker.

Molecules

September 2022

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.

Five new furofurans lignans, Brasesquilignan A-E (), were isolated from the aqueous ethanol extract of Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and GCMS analysis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!