AI Article Synopsis
- Post-intensive care syndrome (PICS) is a growing concern for critically ill COVID-19 patients, but its prevalence and risk factors are not well understood.
- A multicenter study surveyed ventilated COVID-19 patients about their cognitive and emotional health, finding that around 60% experienced PICS months after leaving the ICU.
- Key risk factors identified included the presence of delirium and the length of time on mechanical ventilation, highlighting the need for further support for these patients post-ICU.
Article Abstract
Introduction: Post-intensive care syndrome (PICS) is an emerging problem in critically ill patients and the prevalence and risk factors are unclear in patients with severe coronavirus disease 2019 (COVID-19). This multicenter prospective observational study aimed to investigate the prevalence and risk factors of PICS in ventilated patients with COVID-19 after ICU discharge.
Methods: Questionnaires were administered twice in surviving patients with COVID-19 who had required mechanical ventilation, concerning Barthel Index, Short-Memory Questionnaire, and Hospital Anxiety and Depression Scale scores. The risk factors for PICS were examined using a multivariate logistic regression analysis.
Results: The first and second PICS surveys were obtained at 5.5 and 13.5 months (mean) after ICU discharge, with 251 and 209 patients completing the questionnaires and with a prevalence of PICS of 58.6% and 60.8%, respectively, along with the highest percentages of cognitive impairment. Delirium (with an odds ratio of (OR) 2.34, 95% CI 1.1-4.9, and = 0.03) and the duration of mechanical ventilation (with an OR of 1.29, 95% CI 1.05-1.58, and = 0.02) were independently identified as the risk factors for PICS in the first PICS survey.
Conclusion: Approximately 60% of the ventilated patients with COVID-19 experienced persistent PICS, especially delirium, and required longer mechanical ventilation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571505 | PMC |
| http://dx.doi.org/10.3390/jcm11195758 | DOI Listing |
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