AI Article Synopsis
- Conventional IVF (c-IVF) is declining in popularity as more cases shift toward intracytoplasmic sperm injection (ICSI), especially for non-male-related infertility.
- The review discusses the pros and cons of c-IVF, its success factors, limitations, laboratory differences, and technical advancements.
- It also tackles key issues like maternal age, ovarian reserve, endometriosis, and the debate over the excessive use of ICSI in certain situations, aiming to improve understanding and guidelines in reproductive medicine.
Article Abstract
Conventional IVF (c-IVF) is one of the most practiced assisted reproductive technology (ART) approaches used worldwide. However, in the last years, the number of c-IVF procedures has dropped dramatically in favor of intracytoplasmic sperm injection (ICSI) in cases of non-male-related infertility. In this review, we have outlined advantages and disadvantages associated with c-IVF, highlighting the essential steps governing its success, its limitations, the methodology differences among laboratories and the technical progress. In addition, we have debated recent insights into fundamental questions, including indications regarding maternal age, decreased ovarian reserve, endometriosis, autoimmunity, single oocyte retrieval-cases as well as preimplantation genetic testing cycles. The "overuse" of ICSI procedures in several clinical situations of ART has been critically discussed. These insights will provide a framework for a better understanding of opportunities associated with human c-IVF and for best practice guidelines applicability in the reproductive medicine field.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572455 | PMC |
| http://dx.doi.org/10.3390/jcm11195722 | DOI Listing |
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