MINOCA: One Size Fits All? Probably Not-A Review of Etiology, Investigation, and Treatment.

J Clin Med

Instituto do Coração (InCor), Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-900, Brazil.

Published: September 2022

AI Article Synopsis

  • MINOCA refers to myocardial infarction that occurs without obstructive coronary artery disease, encompassing various causes like atherosclerosis and non-atherosclerotic conditions.
  • Identifying the specific cause of MINOCA is crucial for effective treatment; failing to do so can lead to improper care for patients.
  • Intravascular imaging and cardiac magnetic resonance play key roles in diagnosing and understanding the condition, guiding clinicians in managing MINOCA effectively.

Article Abstract

Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous group of conditions that include both atherosclerotic (coronary plaque disruption) and non-atherosclerotic (spontaneous coronary artery dissection, coronary artery spasm, coronary artery embolism, coronary microvascular dysfunction, and supply-demand mismatch) causes resulting in myocardial damage that is not due to obstructive coronary artery disease. Failure to identify the underlying cause may result in inadequate and inappropriate therapy in these patients. The cornerstone of managing MINOCA patients is to identify the underlying mechanism to achieve the target treatment. Intravascular imaging is able to identify different morphologic features of coronary plaques, while cardiac magnetic resonance is the gold standard for detection of myocardial infarction in the setting of MINOCA. In this review, we summarize the relevant clinical issues, contemporary diagnosis, and treatment options of MINOCA.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571924PMC
http://dx.doi.org/10.3390/jcm11195497DOI Listing

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