Equine Hepacivirus: A Systematic Review and a Meta-Analysis of Serological and Biomolecular Prevalence and a Phylogenetic Update.

Animals (Basel)

National Reference Center for Equine Diseases, Istituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", via Appia Nuova 1411, 00178 Rome, Italy.

Published: September 2022

Viral hepatitis has recently assumed relevance for equine veterinary medicine since a variety of new viruses have been discovered. Equine Hepacivirus (EqHV) is an RNA virus belonging to the family that can cause subclinical hepatitis in horses, occasionally evolving into a chronic disease. EqHV, to date, is considered the closest known relative of human HCV. EqHV has been reported worldwide therefore assessing its features is relevant, considering both the wide use of blood products and transfusions in veterinary therapies and its similitude to HCV. The present review resumes the actual knowledge on EqHV epidemiology, risk factors and immunology, together with potential diagnostics and good practices for prevention. Moreover, adhering to PRISMA guidelines for systematic reviews a meta-analysis of serological and biomolecular prevalence and an updated phylogenetic description is presented as a benchmark for further studies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558973PMC
http://dx.doi.org/10.3390/ani12192486DOI Listing

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Equine Hepacivirus: A Systematic Review and a Meta-Analysis of Serological and Biomolecular Prevalence and a Phylogenetic Update.

Animals (Basel)

September 2022

National Reference Center for Equine Diseases, Istituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", via Appia Nuova 1411, 00178 Rome, Italy.

Viral hepatitis has recently assumed relevance for equine veterinary medicine since a variety of new viruses have been discovered. Equine Hepacivirus (EqHV) is an RNA virus belonging to the family that can cause subclinical hepatitis in horses, occasionally evolving into a chronic disease. EqHV, to date, is considered the closest known relative of human HCV.

View Article and Find Full Text PDF

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