Koller and the dawn of cancer cytogenetics.

Br J Cancer

University of Oxford, Sir William Dunn School of Pathology, South Parks Road, Oxford, OX1 3RE, UK.

Published: February 2023

Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller's conclusions, this study ultimately contributed to the realisation that chromosomal instability is a widespread feature of solid tumours.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938233PMC
http://dx.doi.org/10.1038/s41416-022-01996-zDOI Listing

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