AI Article Synopsis

  • Two cases of multiple evanescent white dot syndrome (MEWDS) were reported following the BNT162b2 mRNA COVID-19 vaccine, highlighting a potential link between the vaccine and ocular issues.
  • A 40-year-old male and a 23-year-old female both experienced blurred vision and findings similar to MEWDS in their left eye after receiving the vaccine.
  • Imaging showed that the eye anomalies resolved on their own within six weeks, pointing to possible inflammation or immune response related to the vaccine as a cause for these effects.

Article Abstract

Purpose: To report two cases of multiple evanescent white dot syndrome (MEWDS) following COVID-19 vaccination with the BNT162b2 mRNA vaccine.

Methods: Two case reports. Case-1: A 40-yo Caucasian male, complained of blurred and decrease of vision in his left eye (OS) one week after the first dose of the BNT162b2 mRNA SARS-CoV-2 vaccine. Funduscopic examination OS showed multiple granular white dots with an aspect of foveal granularity. Case-2: A 23-yo woman also presented with defective and decrease of vision OS. She received her first dose of the BNT162b2 mRNA SARS-CoV-2 vaccine ten days before. Dilated fundus examination OS showed altered macular reflex with an aspect of foveal granularity.

Results: Multimodal imaging showed features of MEWDS in both cases. The anomalies found resolved spontaneously after 6 weeks.

Conclusion: Inflammation and immune dysregulation induced by COVID-19 mRNA vaccine or its adjuvants could be involved in ocular adverse effects.

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Source
http://dx.doi.org/10.1080/09273948.2022.2127782DOI Listing

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