The present contribution provides a tutorial for the estimation of the social relations model (SRM) by means of structural equation modeling (SEM). In the overarching SEM-framework, the SRM without roles (with interchangeable dyads) is derived as a more restrictive form of the SRM with roles (with noninterchangeable dyads). Starting with the simplest type of the SRM for one latent construct assessed by one manifest round-robin indicator, we show how the model can be extended to multiple constructs each measured by multiple indicators. We illustrate a multiple constructs multiple indicators SEM SRM both with and without roles with simulated data and explain the parameter interpretations. We present how testing the substantial model assumptions can be disentangled from testing the interchangeability of dyads. Additionally, we point out modeling strategies that adhere to cases in which only some members of a group can be differentiated with regards to their roles (i.e., only some group members are noninterchangeable). In the online supplemental materials, we provide concrete examples of specific modeling problems and their implementation into statistical software (Mplus, lavaan, and OpenMx). Advantages, caveats, possible extensions, and limitations in comparison with alternative modeling options are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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PLoS One
January 2025
GuiZhou Institute of Subtropical Crops, Guizhou Academy of Agricultural Sciences, Guiyang, China.
Background: Fracture disrupts the integrity and continuity of the bone, leading to symptoms such as pain, tenderness, swelling, and bruising. Rhizoma Musae is a medicinal material frequently utilized in the Miao ethnic region of Guizhou Province, China. However, its specific mechanism of action in treating fractures remains unknown.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
January 2025
Faculdade de Medicina, Laboratório de Parasitologia, Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, Brazil.
This study aimed to standardize qPCR techniques using these molecular markers kDNA and 18S rDNA across three sample types: peripheral blood, guanidine-treated blood, and tissue. The secondary objective is to evaluate the performance of 18S rDNA target in samples from 46 patients with confirmed tegumentary leishmaniasis. After obtaining the standard curve from reference strains with Leishmania, qPCR curves were standardizations and the Cts results of the patient samples were described using abstract measures.
View Article and Find Full Text PDFChem Biodivers
January 2025
University of South China, Department of Gastroenterology, Chuanshan Road, Hengyang, CHINA.
The formation of gastric precancerous-lesions (GPLs) has been identified as a critical step in tumorigenesis, and patients with GPLs have an increased risk of gastric cancer. Magnolol is the primary biphenolic compound in Magnolia officinalis. It possesses various pharmacological properties, such as cardioprotective and neuroprotective properties, and inhibit tumor growth.
View Article and Find Full Text PDFJ R Stat Soc Ser C Appl Stat
January 2025
Department of Biostatistics and Health Data Science, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
The aim of dynamic prediction is to provide individualized risk predictions over time, which are updated as new data become available. In pursuit of constructing a dynamic prediction model for a progressive eye disorder, age-related macular degeneration (AMD), we propose a time-dependent Cox survival neural network (tdCoxSNN) to predict its progression using longitudinal fundus images. tdCoxSNN builds upon the time-dependent Cox model by utilizing a neural network to capture the nonlinear effect of time-dependent covariates on the survival outcome.
View Article and Find Full Text PDFJ Appl Clin Med Phys
January 2025
Medical Physics Section, OHS Department, Hamad Medical Corporation, Doha, Qatar.
Purpose: To evaluate image quality (IQ) of for-processing (raw) and for-presentation (clinical) radiography images, under different exposure conditions and digital image post-processing algorithms, using a phantom that enables multiple detection tasks.
Methods: A modified version of the radiography phantom described in the IAEA Human Health Series No. 39 publication was constructed, incorporating six additional Aluminum (Al) targets of thicknesses both smaller and larger than the standard one.
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