A diastereoselective N-heterocyclic carbene-catalysed reaction between enal and 3-cyano-2-imino-2-chromene is described for accessing a new type of C-functionalized 2-amino-3-cyano-4-chromene. A wide variety of enals and iminochromenes afforded the desired homoenolate addition product 2-amino-4-chromenes in good yields and with moderate to good diastereoselectivities.
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| http://dx.doi.org/10.1039/d2ob01447e | DOI Listing |
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