Curcumin (CUR) has a wide range of applications in functional foods. However, it has some disadvantages such as poor water solubility and stability. To solve these problems, CUR was encapsulated into cochleates with an encapsulation efficiency of 83.66% and a diameter of about 403.9 nm. The study found that the stability of CUR-loaded cochleates (CUR-Cochs) was improved when compared with that of the curcumin-loaded liposomes (CUR-Lipos). Additionally, it showed that the DPPH scavenging ability of CUR-Cochs was equivalent to free CUR. In addition, 3 μM CUR-Cochs could significantly reduce the MDA content and the LDH release, and increased SOD activity in the HO induced NIH3T3 cell oxidative damage model. The expression of Nrf2 and NQO1 proteins were obviously increased in the CUR-Cochs group, indicating that CUR-Cochs could effectively reduce NIH3T3 cell damage caused by HO. The CUR-Cochs could improve the stability of CUR with a desired anti-oxidation ability, which may mean that it is feasible for it to be applied further in functional foods.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d2fo01419j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Expanding Polycyclic Tetramate Macrolactam (PoTeM) Core Structure Diversity by Chemo-Enzymatic Synthesis and Bioengineering.
Angew Chem Int Ed Engl
December 2024
TU Dresden: Technische Universitat Dresden, Faculty of Chemistry and Food Chemistry, Bergstraße 66, 01069, Dresden, GERMANY.
Polycyclic tetramate macrolactams (PoTeMs) represent a growing class of bioactive natural products that are derived from a common tetramate polyene precursor, lysobacterene A, produced by an unusual bacterial iterative polyketide synthase (PKS) / non-ribosomal peptide synthetase (NRPS). The structural and functional diversity of PoTeMs is biosynthetically elaborated from lysobacterene A by pathway-specific cyclizing and modifying enzymes. This results in diverse core structure decoration and cyclization patterns.
View Article and Find Full Text PDFAntiferromagnetic semiconductor nature in a GeS monolayer doped with Mn and Fe transition metals.
Phys Chem Chem Phys
December 2024
Institute of Theoretical and Applied Research, Duy Tan University, Ha Noi 100000, Vietnam.
The absence of intrinsic magnetism in two-dimensional (2D) materials demands functionalization as necessary for broadening their applications. In this work, doping with transition metals (Mn and Fe) is proposed to modify the electronic and magnetic properties of a GeS monolayer. A pristine monolayer is an indirect gap semiconductor with an energy gap of 0.
View Article and Find Full Text PDFNovel foods in the European framework: benefits and risks.
Crit Rev Food Sci Nutr
December 2024
Department of Soil, Plant and Food Sciences (DISSPA), University of Bari Aldo Moro, Italy.
Given the rapidly increasing global demand for food, it is mandatory to consider new sources of nutrients, safe and sustainably produced protein foods to complement the current traditional and limited sources of protein in the human diet. In recent years, a wide range of nontraditional protein foods have been explored, prompting the European Union to legislate on how novel foods can be introduced and traded on the European market to ensure their safety. This review will illustrate the range of novel foods authorized in the EU and their potential impact on human health, highlighting the gaps, the potential risks, and the future research opportunities and perspectives.
View Article and Find Full Text PDFThe prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites.
mSystems
December 2024
Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea.
Onions are well-known vegetables that offer various health benefits. This study explores the impact of onion extracts on gut microbiome using an fecal incubation model and metabolome analysis. Fecal samples were collected from 19 healthy donors and incubated in the presence or absence of onion extracts for 24 h.
View Article and Find Full Text PDFFirst-year dynamics of the anaerobic microbiome and archaeome in infants' oral and gastrointestinal systems.
mSystems
December 2024
Diagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Styria, Austria.
Unlabelled: Recent research provides new insights into the early establishment of the infant gut microbiome, emphasizing the influence of breastfeeding on the development of gastrointestinal microbiomes. In our study, we longitudinally examined the taxonomic and functional dynamics of the oral and gastrointestinal tract (GIT) microbiomes of healthy infants ( = 30) in their first year, focusing on the often-over-looked aspects, the development of archaeal and anaerobic microbiomes. Breastfed (BF) infants exhibit a more defined transitional phase in their oral microbiome compared to non-breastfed (NBF) infants, marked by a decrease in and the emergence of anaerobic genera such as .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!