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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548635 | PMC |
| http://dx.doi.org/10.3389/fpsyt.2022.1021926 | DOI Listing |
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Objectives: The current gold standard for immunofluorescent (IF) visualization of neuromuscular junctions (NMJs) in muscle utilizes frozen tissue sections with fluorescent conjugated antibodies to demarcate neurons and IF alpha-bungarotoxin (α-BTX) to demarcate motor endplates. Frozen tissue sectioning comes with inherent inescapable limitations, including cryosectioning artifact and limited sample shelf-life. However, a parallel approach to identify NMJs in paraffin-embedded tissue sections has not been previously described.
View Article and Find Full Text PDFEpithelial immunotherapy for food allergy in children: a systematic review and meta-analysis.
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Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Objectives: Traditional methods of treating allergies primarily revolve around avoiding allergens and promptly using rescue medications when allergic symptoms occur. However, this approach is known for its inefficiency and limited success in achieving long-term relief. Our aim was to conduct a comprehensive analysis of previously published randomized controlled trials (RCTs) that explore the effectiveness and safety of epicutaneous immunotherapy (EPIT) as a means to manage food allergies in children.
View Article and Find Full Text PDFEffective Acupuncture in Treating Decade-Long Occipital Neuralgia in an Elderly Patient.
Am J Case Rep
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Department of Acupuncture and Moxibustion, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
BACKGROUND Occipital neuralgia is a headache caused by irritation or damage to the occipital nerves situated at the rear of the head and neck. It is characterized by sharp, stinging, or electric shock-like pain in the distribution area of the occipital nerve, which often causes patients acute pain and discomfort. To report on the feasibility of non-drug therapy in addressing this condition, we present a case report showcasing the remarkable improvement in occipital neuralgia symptoms achieved with a single acupuncture session, followed by a brief period of care.
View Article and Find Full Text PDFImmunological challenges and opportunities in glioblastoma multiforme: A comprehensive view from immune system lens.
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Department of Pharmacy, Birla Institute of Technology and Sciences, Pilani, Rajasthan 333031, India. Electronic address:
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View Article and Find Full Text PDFUnderstanding health-related quality of life after hypospadias repair: A qualitative study with pre-adolescent males and parents.
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Department of Pediatrics, Division of Psychology, Texas Children's Hospital and Baylor College of Medicine, Houston, TX, USA.
Article Synopsis
- Hypospadias is a birth defect affecting 1 in 200 males in the U.S., leading to significant long-term complication rates and impacting psychological, social, and sexual health.
- A qualitative study was conducted involving interviews with 8-12-year-old boys with hypospadias and their parents to explore health-related quality of life and care priorities.
- Key findings revealed three main themes: concerns about physical aspects (Penile Factors), psychological and social pressures (Psychosocial Concerns), and expectations regarding medical care, highlighting differences in perspectives between children and parents, especially among those from disadvantaged backgrounds.
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