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Interobserver reliability of Pirani scoring for idiopathic clubfoot in walking-age children.
J Pediatr Orthop B
January 2025
Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Delhi, India.
Pirani scoring system is one of the most commonly used tools to assess the initial deformity, monitor the treatment progression, and identify relapse in clubfoot. The method has been demonstrated to correlate well with the sequential correction of deformity for children under age 1 year. We conducted a study to examine the interobserver reliability of Pirani scores in children of walking-age.
View Article and Find Full Text PDFSleep-disordered breathing and cardiometabolic and inflammatory markers in children with overweight/obesity: The role of cardiorespiratory fitness.
Pediatr Obes
January 2025
Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.
Objectives: To investigate the association of sleep-disordered breathing (SDB) severity with cardiometabolic and inflammatory markers independently of the adiposity levels; and to explore the role of cardiorespiratory fitness in these associations in children with overweight/obesity.
Methods: A total of 109 children aged 8-11 years with overweight/obesity were included in this cross-sectional study. SDB was assessed using a scale of the reduce version of the Paediatric Sleep Questionnaire.
Routine Fundoscopy: Unravelling Undiagnosed Significant Coarctation of the Aorta.
Cureus
December 2024
Ophthalmology, Father Muller Medical College, Mangalore, IND.
A 10-year-old boy was brought to the outpatient department with complaints of diminished vision for two years. On examination, the best-corrected visual acuity (BCVA) in oculus dexter (OD) was 20/40 and in oculus sinister (OS) was 20/80. The patient was dilated for routine fundoscopy, which revealed grade IV hypertensive retinopathy changes in both eyes, with a macular fan in the left eye.
View Article and Find Full Text PDFEffectiveness of school-based oral health education interventions on oral health status and oral hygiene behaviors among schoolchildren: an umbrella review.
Evid Based Dent
January 2025
Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Objective: To summarize evidence of the effectiveness of school-based oral health education interventions on oral health status and oral hygiene behaviors among schoolchildren.
Methods: A comprehensive search was conducted across seven databases MEDLINE Ovid, Google Scholar, Web of Science, Scopus, EBSCO-APA PsycInfo, ProQuest, and CINAHL, with two independent reviewers screening titles and abstracts including full texts. Data extraction procedure and quality appraisal of this umbrella review adhered to the JBI critical appraisal checklist.
Protease-activated receptor 1 in the pathogenesis of cystic fibrosis.
BMJ Open Respir Res
January 2025
Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Background: The most common cause of death in those with cystic fibrosis (CF) is respiratory failure due to bronchiectasis resulting from repeated cycles of respiratory infection and inflammation. Protease-activated receptor 1 (PAR1) is a cell surface receptor activated by serine proteases including neutrophil elastase, which is recognised as a potent modulator of inflammation. While PAR1 is known to play an important role in regulating inflammation, nothing is known about any potential role of this receptor in CF pathogenesis.
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