The impact of family factors, particularly the sibling status, on the development and course of eating disorders has been rarely investigated.Therefore, the aimof the present study was to assess a putative association between sibling status and self-rated family dysfunctionality in a large sample of study participants with bulimia nervosa and anorexia nervosa. A total cohort of n = 568 outpatients aged twelve years and older, of whomhalf had the diagnosis of anorexia (n = 288, 50.7 %), was assessed for self-rated family dysfunctionality using the well-validated German General Family Questionnaire (FB-A), while the symptom level (Global Severity Index) was determined using the SCL-90-Rsymptomchecklist. Patientswith anorexiaweremore frequently only children compared to the bulimia group who had generallymore siblings (22.6%vs. 14.4%, p = 0.012). In patients with bulimia nervosa, bivariate analyses revealed a significant positive association between the presence of siblings and the degree of family dysfunctionality (only child: 33.6 ± 17.6, sibling child: 39.3 ± 15.5, p = 0.043). Linear regressionmodels adjusted for age, body-mass index, parents living in separation, and the Global Severity Index (GSI) confirmed a significant association between higher family dysfunctionality as a dependent variable and sibling status (beta = 0.163, 95%confidence interval [CI] = 1.431; 12.774, p = 0.014).No such relationship was found in the anorexia group (p = 0.418).The differential associations between sibling status and self-rated family dysfunctionality found for the two eating-disorder entities may indicate differences in the pathogenesis of anorexia and bulimia nervosa.
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http://dx.doi.org/10.13109/prkk.2022.71.6.528 | DOI Listing |
Food Sci Nutr
December 2024
Chemistry Department, College of Education Salahaddin University Erbil Iraq.
Evaluation of of the family Boraginaceae during previous investigations determined numerous therapeutic potentials against inflammatory-related diseases. The present study evaluates the phytochemical, acute toxicity, and hepatoprotective effects of methanolic extracts of (MEAL) against thioacetamide (TAA)-induced liver injury in rats. The phytochemical profiling of MEAL followed a Folin-Ciocalteu and 10% AlCl3 procedure using a spectrophotometer.
View Article and Find Full Text PDFOncogene
August 2024
Institute of Anatomy and Cell Biology, Universität Würzburg, Koellikerstrasse 6, 97070, Würzburg, Germany.
Blood vessels in tumors are often dysfunctional. This impairs the delivery of therapeutic agents to and distribution among the cancer cells. Subsequently, treatment efficacy is reduced, and dose escalation can increase adverse effects on non-malignant tissues.
View Article and Find Full Text PDFRev Med Chil
August 2023
Departamento de Trabajo Social, Universidad de Barcelona, Barcelona, España.
Background: Loneliness is one of the most recurrent public health problems in older people. However, there is little data available in Chile on its prevalence in people over 60 years of age living in rural areas and belonging to native or Afro-descendant groups.
Aim: To examine the prevalence of loneliness among older people living in rural areas by ethnic group and to analyze the socio-demographic, family, and health variables related to loneliness.
Ann Clin Lab Sci
May 2024
Division of Community and Family Medicine, Jichi Medical University, Shimotsuke-City, Tochigi, Japan
Objective: Familial hypercholesterolemia (FH) is characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C) and cardiovascular disease (CVD). Although the role of LDL-C in FH has been studied, the contribution of high-density lipoproteins (HDL) to CVD in FH remains unknown. This study aimed at highlighting the role of HDL in FH.
View Article and Find Full Text PDFNurs Rep
May 2024
Nursing Department, Faculty of Healthcare Sciences, University of La Laguna, 38200 Santa Cruz de Tenerife, Spain.
One of the priorities in family and community care is the epidemiological surveillance of the care needs and dysfunctionality present in populations of highly complex chronic patients (HCCPs) using standardised nursing languages. The aim of this study is to establish the prevalence of care needs and dysfunctionality among HCCPs in a specific health area by municipalities and geographical areas (metropolitan, north, and south) while verifying correlations with sociodemographic, financial, and health characteristics. This is an epidemiological, observational, descriptive, cross-sectional study carried out with a sample of 51,374 HCCPs, whose data were grouped into 31 municipalities.
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