Fulminant Sepsis and Perinatal Death at 23 Weeks Due to .

Fetal Pediatr Pathol

Department of Obstetrics and Pediatrics, Neonatal Intensive Care Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Published: June 2023

is a gram-negative anaerobe, a constituent of the oral microflora, responsible for chronic periodontal diseases. We describe a preterm infant with premature rupture of membranes at 23 weeks of gestational age due to . The newborn died soon after birth. Placental histopathology showed severe necrotizing chorioamnionitis and funisitis with gram-negative bacilli. After autopsy, was microbiologically isolated from the lung. The mother had dental hygiene 1 day before delivery, presenting mild and diffuse gingivitis. At admission, she had leukocytosis, foul-smelling vaginal discharge, but no fever. This case highlights the possibility of spreading from oral cavity after a dental procedure to the placenta with chorioamnionitis and fetal infection. This raises the question of whether dental procedures during pregnancy should be accompanied by prophylactic antibiotics.

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Source
http://dx.doi.org/10.1080/15513815.2022.2131487DOI Listing

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