Bisattelited supernumary chromosomes, identified as inv dup(15)s, were detected at a prevalence of 8/1000 among institutionalized, mentally retarded (non-Down syndrome) males. This finding suggests that the inv dup(15) contributes significantly to the etiology of mental retardation among institutionalized individuals.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1399-0004.1987.tb02837.xDOI Listing

Publication Analysis

Top Keywords

mentally retarded
8
identified inv
8
inv dup15
8
supernumary marker
4
marker chromosomes
4
chromosomes mentally
4
retarded population
4
population identified
4
dup15 bisattelited
4
bisattelited supernumary
4

Similar Publications

Aims And Background: Fostering a positive dental attitude in children to enhance their oral health status and engaging them positively throughout their dental experience is the cornerstone of pediatric dentistry practices. The behavior of the child in a dental setting depends upon their emotional, psychological, and mental developmental state. Children with special health needs tend to have more anxiety than healthy children.

View Article and Find Full Text PDF

Compared to the general population, individuals with Down syndrome carry a much higher genetic risk of developing early onset Alzheimer's dementia. This leads to unique challenges and the need for a targeted patient journey.In a qualitative interview study with medical professionals, patient organisations and formal and informal care persons, we assessed barriers within the medical care process of this patient group as well as current approaches to overcome these problems.

View Article and Find Full Text PDF

Background: Persons with intellectual and/or developmental disabilities (IDD) are a growing population, frequently living with complex health conditions and unmet healthcare needs. Traditional clinical practice and research methods and measures may require adaptation to reflect their preferences.

Objective: The perspectives of people with IDD, caregivers/partners, and clinicians were obtained to provide insight into factors contributing to the health and wellness of people with IDD.

View Article and Find Full Text PDF

Background: Restricted and repetitive behavior (RRB) is a core symptom of autism spectrum disorder (ASD). The structure of RRB subcategories and their relationship with atypical sensory processing in Japan are not well understood. This study examined subcategories of the RRB in Japanese children with ASD and explored their relationship with sensory processing.

View Article and Find Full Text PDF

Background: Individuals with Down syndrome are an at-risk population for severe COVID-19 outcomes, due to genetic predispositions and comorbidities. The current study focused on differences between persons with and without Down syndrome regarding age and severity of disease.

Method: We used medical statistics to compare patients with and without Down syndrome who were admitted to Swiss hospitals (2020 and 2022) with a COVID-19 diagnosis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!