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APC 4099 has broad-spectrum antimicrobial activity against both bacteria and fungi and produces several antimicrobial peptides, including the novel circular bacteriocin safencin E.
Appl Environ Microbiol
December 2024
School of Microbiology, University College Cork, Cork, County Cork, Ireland.
Unlabelled: APC 4099, isolated from bees' gut, has been identified as a promising candidate for food biopreservation. Antimicrobial activity screening revealed a broad-spectrum inhibition potential, ranging from gram-positive pathogenic bacteria to fungi responsible for food spoilage. Genomic analysis identified biosynthetic gene clusters coding for several antimicrobial peptides and secondary metabolites.
View Article and Find Full Text PDFQuantitative Histopathology Analysis Based on Label-free Multiphoton Imaging for Breast Cancer Diagnosis and Neoadjuvant Immunotherapy Response Assessment.
Int J Biol Sci
January 2025
Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Accurate diagnosis and assessment of breast cancer treatment responses are critical challenges in clinical practice, influencing patient treatment strategies and ultimately long-term prognosis. Currently, diagnosing breast cancer and evaluating the efficacy of neoadjuvant immunotherapy (NAIT) primarily rely on pathological identification of tumor cell morphology, count, and arrangement. However, when tumors are small, the tumors and tumor beds are difficult to detect; relying solely on tumor cell identification may lead to false negatives.
View Article and Find Full Text PDFmeningitis in a patient with newly diagnosed acquired immunodeficiency syndrome from Sikkim, India.
Curr Med Mycol
May 2024
Department of Microbiology, Sikkim Manipal Institute of Medical Science, Gangtok, India.
Background And Purpose: infections in India have shifted, with an increase in the incidence rate of invasive candidiasis, particularly due to non- species. The central nervous system infections by are sparsely reported and more understanding and research is needed regarding these infections.
Case Report: This study reported an unusual case of meningitis in a middle-aged female with pulmonary tuberculosis and newly diagnosed acquired immunodeficiency syndrome with a low cluster of differentiation 4 count (12 cells/mm).
as an emerging rare cause of septicemia among neonates and children in Western Uttar Pradesh: A case series.
Curr Med Mycol
May 2024
Department of Microbiology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Background And Purpose: is a recently emerging nosocomial fungal pathogen. Candidemia is the fourth most prevalent cause of bloodstream Infections with mortality rates varying from 5-71%.
Materials And Methods: This was a retrospective study conducted at Uttar Pradesh University of Medical Sciences, Etawah, India, from September 2023 to February 2024.
Emotion recognition using multi-scale EEG features through graph convolutional attention network.
Neural Netw
December 2024
The school of Electrical and Information Engineering, Tianjin University, Tianjin 300072, China. Electronic address:
Emotion recognition via electroencephalogram (EEG) signals holds significant promise across various domains, including the detection of emotions in patients with consciousness disorders, assisting in the diagnosis of depression, and assessing cognitive load. This process is critically important in the development and research of brain-computer interfaces, where precise and efficient recognition of emotions is paramount. In this work, we introduce a novel approach for emotion recognition employing multi-scale EEG features, denominated as the Dynamic Spatial-Spectral-Temporal Network (DSSTNet).
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