An n-order marker field is a special binary matrix whose n×n subregions are all distinct from each other in four orientations. It is commonly used to guide the composing process of position-sensing markers, which can be detected and identified in a camera image with very limited scope or severe visibility problems. Despite the advantages, position-sensing markers are rare and overlooked because generating marker fields is difficult. In this article, we broaden the definition of marker field, making it more powerful and flexible. Then, we propose bWFC (binary wave function collapse) and its high-speed version, fast-bWFC, to solve the generation problem. The methods are packaged into an open-sourced toolkit named HydraMarker, with which, users not only can generate marker fields on laptops within a short period of time, but also can highly customize them: preset values; fields and subregions in any shape; multifold local uniqueness. Comparative results indicate that the proposed method has superior efficiency, quality, and capability. It makes marker field generation accessible to common marker designers, opening up more possibilities for fiducial markers.
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http://dx.doi.org/10.1109/TPAMI.2022.3212862 | DOI Listing |
Background: OLX-07010 is an oral small molecule inhibitor of tau self-association that prevented the accumulation of tau aggregates in the htau mouse model expressing wild type human CNS tau isoforms and in P301L tau JNPL3 mice using chronic treatment by administration in diet (Davidowitz et al., 2020, PMID: 31771053; 2023 PMID:37556474). A therapeutic study of JNPL3 mice with chronic treatment from 7-12 months of age inhibited the progression of tau aggregation and improved motor coordination.
View Article and Find Full Text PDFJ Cancer
January 2025
Department of Urology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Exploration of molecular markers is an ongoing focus in the field of bladder cancer research. Based on data from public databases, was identified as upregulated in bladder urothelial carcinoma (BLCA); however, its exact function and regulatory mechanism in this context remain unclear. To investigate the clinical implications of , we examined its levels in 90 BLCA and adjoining normal tissue samples.
View Article and Find Full Text PDFBMC Biol
January 2025
Institute of Biology Leiden, Leiden University, Sylvius Laboratory, Sylviusweg 72, 2333 BE, Leiden, The Netherlands.
Background: Regeneration is the replacement of lost or damaged tissue with a functional copy. In axolotls and zebrafish, regeneration involves stem cells produced by de-differentiation. These cells form a growth zone which expresses developmental patterning genes at its apex.
View Article and Find Full Text PDFPlant Genome
March 2025
INRAE, CNRS, AgroParisTech, GQE-Le Moulon, Université Paris-Saclay, Gif-sur-Yvette, France.
Classical genomic prediction approaches rely on statistical associations between traits and markers rather than their biological significance. Biologically informed selection of genomic regions can help prioritize polymorphisms by considering underlying biological processes, making prediction models robust and accurate. Gene ontology (GO) terms can be used for this purpose, and the information can be integrated into genomic prediction models through marker categorization.
View Article and Find Full Text PDFExpert Rev Mol Diagn
January 2025
Department of Electronics and Communication Engineering, IIITDM Kancheepuram, Chennai, India.
Introduction: Cancer ranks as the second most prevalent cause of death worldwide, responsible for approximately 9.6 million deaths annually. Approximately one out of every six deaths is caused by cancer.
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