Introduction: Syphilitic balanitis of Follmann (SBF) is a rare condition of primary syphilis which is characterized by any kind of balanitis with or without chancre on the penis combined with the presence of swollen inguinal lymph nodes confirmed by the finding of Treponema pallidum in the lesions or by the positive serological syphilitic testing. Timely identification of the SBF is very important in properly treating the disease stopping the spread of syphilis.

Case Presentation: A 42year-old heterosexual male patient came to our clinic and complained of a painless, hard erythema nodule with a whitish scale in his coronal sulcus of the penis for about a week. The dermatologic examination revealed an infiltrative, hard erythematous lesion surrounding the coronal sulcus of the patient's penis, with mild erosion and a small amount of exudation. There was a whitish pseudomembrane-like covering on the surface of the erythematous lesion in the coronal sulcus, which is mimicked as candidal balanitis. The result of the fungus microscopic examination was negative, while the laboratory findings showed positive results in serologic syphilitic testing. The patient was diagnosed with primary syphilis and intramuscularly treated with a dose of benzylpenicillin of 2.4 million units. The patient's skin lesions disappeared completely 60 days after penicillin treatment.

Conclusion: To our knowledge, this is the first SBF case reported in China. Syphilitic balanitis of Follmann may have variable clinical appearances. We emphasize that when balanitis with risky sexual activities or with sexually transmitted diseases, the diagnosis of SBF should be kept in mind.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533062PMC
http://dx.doi.org/10.3389/fmed.2022.958456DOI Listing

Publication Analysis

Top Keywords

primary syphilis
12
syphilitic balanitis
12
balanitis follmann
12
coronal sulcus
12
syphilitic testing
8
erythematous lesion
8
balanitis
6
syphilitic
5
syphilis chancre
4
chancre case
4

Similar Publications

Seroprevalence of specific antibodies to Treponema pallidum in blood donors with DNA confirmation of seropositivity.

Cell Mol Biol (Noisy-le-grand)

January 2025

Swedish Board Member of General Surgery, Kurdistan Higher Council of Medical Specialties, Erbil, Iraq.

The rising global incidence of syphilis underscores the risk of transmission through blood transfusions. Treponema pallidum, the pathogen responsible for syphilis, represents a major public health challenge. Accurate detection is essential for controlling the disease, particularly in asymptomatic blood donors.

View Article and Find Full Text PDF

The diagnostic process and discrimination of mucosal lesions present a formidable challenge for numerous clinicians, primarily attributable to the common overlap of clinical manifestations observed across various categories, including infectious, autoimmune, connective tissue, and systemic vascular inflammatory diseases. In cases of mucosal lesions, syphilis presents distinctive characteristics that can help clinicians differentiate it from other conditions. The most common manifestation of primary syphilis is mostly a painless, firm, indurated ulcer known as a chancre, which typically appears at the site of inoculation, with enlargement of regional lymph nodes.

View Article and Find Full Text PDF

Although herpes simplex virus, Epstein-Barr virus, and hemophagocytic lymphohistiocytosis are known causes of severe acute liver injury with or without liver failure, these diseases occur almost exclusively in immunocompromised and elderly patients. We report a case of an immunocompetent young man with no medical history who presented with a subacute cough and persistent fevers in the setting of a penile chancre. He was found to have severely elevated liver chemistries and was subsequently diagnosed with hemophagocytic lymphohistiocytosis because of disseminated herpes simplex virus type 1 and Epstein-Barr virus coinfection.

View Article and Find Full Text PDF
Article Synopsis
  • Doxycycline postexposure prophylaxis (doxyPEP) effectively reduces the incidence of bacterial sexually transmitted infections (STIs) in those assigned male at birth, although practical data is limited.
  • This study analyzed electronic health records of HIV PrEP users from Kaiser Permanente Northern California to assess the uptake of doxyPEP and its impact on STI rates before and after its initiation.
  • Out of 11,551 HIV PrEP users, 19.5% received doxyPEP, with a notable percentage having an STI prior; findings suggest changes in STI positivity rates among those who started doxyPEP versus those who did not.
View Article and Find Full Text PDF

Doxycycline Postexposure Prophylaxis and Sexually Transmitted Infection Trends.

JAMA Intern Med

January 2025

San Francisco Department of Public Health, San Francisco, California.

Article Synopsis
  • The rising rates of sexually transmitted infections (STIs) have heightened health concerns, prompting research into doxycycline postexposure prophylaxis (doxyPEP) as a preventive strategy for bacterial STIs.
  • A study was conducted in San Francisco to evaluate how the introduction of doxyPEP guidelines affected reported cases of chlamydia, gonorrhea, and early syphilis among men who have sex with men (MSM) and transgender women.
  • Results revealed a significant decrease in STI cases among these populations after the implementation of doxyPEP guidelines, with chlamydia and early syphilis cases declining by 6.58% and 2.68% per month, respectively, compared to
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!