Magnetic Resonance Imaging (MRI) is a safe and versatile diagnostic tool for intracranial imaging, however it is also one of the most expensive and specialized making it scarce in low- to middle-income countries (LMIC). The affordability and portability of low-field MRI offers the potential for increased access to brain imaging for diseases like Hydrocephalus in LMIC. In this tutorial style work, we show the design of a low powered and low cost radio frequency chain of electronics to be paired with a previously reported prepolarized low-field MRI for childhood hydrocephalus imaging in sub-Saharan Africa where the incidence of this condition is high. Since the Larmor frequency for this system is as low as 180 kHz, we are able to minimize the impedance of the transmit coil to 5 ohms rather than match to 50 ohms as is traditionally the case. This reduces transmit power consumption by a factor of 10. We also show the use of inexpensive and commonly available animal enclosure fencing ("chicken wire") as a shield material at this frequency and compare to more traditional shield designs. These preliminary results show that highly portable and affordable low-field MRI systems could provide image resolution and signal-to-noise sufficient for planning hydrocephalus treatment in areas of the world with substantial resource limitations. Employment of these technologies in sub-Saharan Africa offers a cost-effective, sustainable approach to neurological diagnosis and treatment planning in this disease burdened region.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536774 | PMC |
http://dx.doi.org/10.3389/fphy.2021.727536 | DOI Listing |
Foods
January 2025
Heyuan Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Heyuan 517000, China.
This study investigated the impact of glycerol monooleate (MO) at varying levels (0.3%, 0.6%, 0.
View Article and Find Full Text PDFPediatr Radiol
January 2025
Research Department of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, SE1 7EH, UK.
Background: Motion correction methods based on slice-to-volume registration (SVR) for fetal magnetic resonance imaging (MRI) allow reconstruction of three-dimensional (3-D) isotropic images of the fetal brain and body. However, all existing SVR methods are confined to research settings, which limits clinical integration. Furthermore, there have been no reported SVR solutions for low-field 0.
View Article and Find Full Text PDFBioengineering (Basel)
January 2025
Promaxo Inc., Oakland, CA 94607, USA.
This study evaluates the feasibility of using Haralick texture analysis on low-field, T2-weighted MRI images for detecting prostate cancer, extending current research from high-field MRI to the more accessible and cost-effective low-field MRI. A total of twenty-one patients with biopsy-proven prostate cancer (Gleason score 4+3 or higher) were included. Before transperineal biopsy guided by low-field (58-74mT) MRI, a radiologist annotated suspicious regions of interest (ROIs) on high-field (3T) MRI.
View Article and Find Full Text PDFSci Data
January 2025
National Clinical Research Center for Child Health, National Children's Regional Medical Center, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Recently, imaging investigation of brain development has increasingly captured the attention of researchers and clinicians in an attempt to understand the link between the brain and behavioral changes. Although high-field MR imaging of infants is feasible, the necessary customizations have limited its accessibility, affordability, and reproducibility. Low-field MR, as an emerging solution for scrutinizing developing brain, has exhibited its unique advantages in safety, portability, and cost-effectiveness.
View Article and Find Full Text PDFZ Med Phys
January 2025
Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland; Department of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland.
Purpose: This study aims to evaluate the feasibility of structural sub-millimeter isotropic brain MRI at 0.55 T using a 3D half-radial dual-echo balanced steady-state free precession sequence, termed bSTAR and to assess its potential for high-resolution magnetization transfer imaging.
Methods: Phantom and in-vivo imaging of three healthy volunteers was performed on a low-field 0.
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