AI Article Synopsis
- - The study evaluates the effectiveness of oseltamivir, an antiviral drug, for treating COVID-19 in 544 patients from Imam Khomeini Hospital in Iran between February and April 2020.
- - Results showed that while oseltamivir did not significantly reduce hospitalization time or improve survival rates, it was associated with an increase in lymphocyte count and a decrease in C-reactive protein levels.
- - Overall, the findings suggest that oseltamivir does not enhance treatment outcomes for COVID-19 patients in terms of hospitalization duration or survival.
Article Abstract
Introduction: Coronavirus disease 2019 (COVID-19) is the most critical issue in nowadays medicine. We aimed to evaluate the use and therapeutic outcomes of oseltamivir, an antiviral drug for patients with COVID-19.
Materials And Method: In an observational study conducted at Imam Khomeini Hospital in Amol, Iran, data for 544 patients with laboratory and CT scan result confirmed COVID-19 were retrospectively collected between February 24th and April 13th 2020. To compare the characteristics of patients based on gender, the chi-square test was used. Logistic regression was used to evaluate the effect of oseltamivir on the outcome of treatment. Logrank test were used to compare the length of hospital stay in people treated with oseltamivir and drugs other than oseltamivir.
Results: Kaplan-Meier and logrank test showed no significant reduction in hospitalization time and survival rate following treatment with oseltamivir. However, a significant increase in lymphocytes count and reduction of C-reactive protein (CRP) level detected.
Conclusion: Administration of oseltamivir for patients with COVID-19 didn't show any improvement in hospitalization duration and survival rate.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531663 | PMC |
| http://dx.doi.org/10.1016/j.vacun.2022.09.077 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!