Epidemiology, Diagnosis, Pathophysiology, and Initial Approach to Heart Failure with Preserved Ejection Fraction.

Cardiol Clin

University of Michigan Frankel Cardiovascular Center, 1500 East Medical Center Dr., SPC 5853, Ann Arbor, MI 48109, USA.

Published: November 2022

AI Article Synopsis

  • Heart failure with preserved ejection fraction (HFpEF) is becoming more common but is difficult to diagnose because it shares symptoms with other health issues.
  • It is recognized as a systemic syndrome influenced by inflammation from other comorbid conditions, rather than just a heart problem.
  • The review outlines the prevalence, diagnostic methods, and underlying causes of HFpEF and suggests ways to manage patients suspected of having it.

Article Abstract

Heart failure with preserved ejection fraction (HFpEF) is common and increasing in prevalence. Despite this, HFpEF is challenging to diagnose due in part to its shared clinical features with other comorbid conditions. HFpEF is now understood as a systemic syndrome, often driven by pro-inflammatory comorbidities, rather than solely a cardiac disease. This review summarizes the epidemiology, diagnostic criteria, and pathophysiology of HFpEF and proposes a clinical approach for patients suspected of having or diagnosed with HFpEF.

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Source
http://dx.doi.org/10.1016/j.ccl.2022.07.001DOI Listing

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