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| http://dx.doi.org/10.1016/j.cger.2022.07.010 | DOI Listing |
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Analysis of the pattern of drug use using WHO core drug indicators among general OPD patients in rural Puducherry.
J Family Med Prim Care
November 2024
Department of Community Medicine, Indira Gandhi Medical College and Research Institute, Puducherry, India.
Background: Prescription auditing is a crucial tool for evaluating a range of concerns, including injectable usage, polypharmacy, the use of generic names, and the quality of treatment given to patients in primary care facilities. The objective of the study was to assess, using WHO core drug use indicators, the drug use patterns of general outpatients (OPD) at a rural healthcare facility.
Materials And Methods: A cross-sectional study was conducted in a rural peripheral health centre in Puducherry for a period of one year from September 2019 to August 2020.
Efficacy of quality improvement interventions on antibiotic prescription practices for ventilator-associated pneumonia at a tertiary care centre: a prospective pre-post interventional study.
BMJ Open Qual
December 2024
Department of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Background: Ventilator-associated pneumonia (VAP) is a prevalent nosocomial infection in the intensive care unit (ICU), significantly increasing patient morbidity, mortality, and healthcare costs. Effective management is essential, particularly in the context of antimicrobial resistance and the frequent use of antibiotics in ICUs.
Methods: This prospective pre-post interventional study was conducted in the medical ICU of a tertiary care centre, over 6 months.
Clozapine treatment continues to be recognized as the gold standard for managing treatment-resistant schizophrenia. Combining clozapine with other antipsychotics (i.e.
View Article and Find Full Text PDFPrevalence of heart failure pharmacotherapy utilisation, frailty and adverse drug events among hospitalised adults older than 75 years: a multicentre cross-sectional study.
Intern Med J
December 2024
Laboratory of Ageing and Pharmacology, Kolling Institute, Northern Sydney Local Health District, Sydney, New South Wales, Australia.
Background: Optimal heart failure (HF) pharmacotherapy (guideline-directed medical therapy and diuretics) in older people with frailty is uncertain due to limited evidence.
Aims: To evaluate utilisation of HF pharmacotherapy and prevalence of polypharmacy, adverse drug events (ADEs), falls, delirium, renal impairment and duration of hospitalisation in older inpatients, according to frailty.
Methods: A retrospective cross-sectional study of the TO HOME cohort of 2000 inpatients ≥75 years admitted for ≥48 h to rehabilitation, geriatric or general medicine from 1 July 2016 to 30 June 2017 across six hospitals in Sydney, Australia.
Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders.
Int J Clin Pharm
December 2024
School of Pharmacy and Life Sciences, Applied Sciences and Public Health, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7GJ, UK.
Background: Inappropriate polypharmacy arises through many factors including deficiencies in prescribing processes. Most research has focused on solutions at the clinician/patient levels with less at the organisational level.
Aim: To explore key stakeholder identified barriers and facilitators to implementation of an organisational level polypharmacy management framework.
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