Bioelectronic medicine has tremendous potential in biomedical sector including oncology research, research on biomechanical and chemical properties of cells and biomaterials, healing bone tissue using electromagnetic fields, and understanding bioelectrical properties of aging. Bioelectronic medicine uses electricity to alter the body's electrical communication systems in order to treat various illnesses. The bioelectric circuits produce an endogenous electric field and a resting voltage when the cells are functioning and communicating. Oncology research has gained considerable interest focused on the development of emerging bioelectric cancer medicines. Reprogrammable circuits that underlie cancer, regeneration, and embryogenesis are known as bioelectric signalling. It is possible to create new therapeutic options to slow the spread of cancer by taking advantage of the bioelectric properties of cancer cells. The treatment of cancer may benefit from bioelectronic medicine. We looked into the value of bioelectrical energy in the fight against disease. This communication also covered the methods for therapeutically controlling this fatal illness. It is crucial to identify or measure the electrical activity of body cells in order to control or modify bioelectricity and bring about changes in cell structure. Knowledge of the cell-to-cell ionic interaction, faradaic processes, and their function in developing cancer phenotypes may improve cancer treatment approaches. With new evidence supporting an electrical mechanism that promotes this phenomenon, the data may also help us understand cancer metastasis better.
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http://dx.doi.org/10.1016/j.bbcan.2022.188808 | DOI Listing |
Adv Healthc Mater
January 2025
Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, 730050, China.
Implantation of a mesh loaded with mesenchymal stem cells (MSCs) is a common approach for the treatment of pelvic organ prolapse (POP). The mesh provides effective support to pelvic floor, enhancing muscle contraction of pelvic organs while reducing inflammation. In this study, a fully degradable mesh is designed for the treatment of POP, utilizing MSCs stimulated by a galvanic battery-powered electric field.
View Article and Find Full Text PDFDaru
December 2024
Lloyd School of Pharmacy, 201306, Greater Noida, Uttar Pradesh, India.
Objectives: Electroceuticals refers to the constantly growing disciplines of bioelectric and bioelectronic medication. These include a broad variety of devices that have been invented and are now being utilized in medical implants, wearable medical electronics, and bioelectronics. The primary aim of this study is to encompass several facets of electroceuticals, their applications, and recent advancements in the field of medical challenges.
View Article and Find Full Text PDFOsteoarthr Cartil Open
March 2025
Section of Rheumatology Boston University Chobanian & Avedisian School of Medicine, United States.
Objective: Transcutaneous auricular vagus nerve stimulation () may be an innovative treatment for symptoms of knee osteoarthritis (OA) due to possible shared pathological mechanisms between diminished parasympathetic function, central pain mechanisms, and knee pain. Thus, we sought to test the safety and preliminary efficacy of tVNS in people with knee OA.
Design: A pilot trial in which participants received a 60-min tVNS was conducted.
Res Sq
December 2024
Department of Electrical and Computer Engineering, Rice University, 6100 Main St, Houston, TX, 77005.
Wireless communication technologies for bioelectronic implants enable remote monitoring for diagnosis and adaptive therapeutic intervention without the constraints of wired connections. However, wireless data uplink from millimeter-scale devices deep in the body struggles to achieve low power consumption while maintaining large misalignment tolerances. Here, we report a passive wireless backscatter communication system based on magnetoelectric transducers that consumes less than 0.
View Article and Find Full Text PDFThe Stimulating Peripheral Activity to Relieve Conditions (SPARC) program is a U.S. National Institutes of Health (NIH) funded effort to enhance our understanding of the neural circuitry responsible for visceral control.
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