AI Article Synopsis
- Highlights the importance of recognizing VEXAS syndrome in patients with unexplained inflammation, anemia, and related symptoms.
- VEXAS usually affects older males (over 60) and is characterized by inflammation and macrocytic anemia.
- The review discusses the pathogenesis, symptoms, diagnosis, and treatment options for VEXAS, aiming to improve awareness among clinicians.
Article Abstract
This review aims to make clinicians aware of the newly described syndrome, VEXAS. VEXAS should become an obvious differential diagnosis in cases of unexplained inflammation, anemia, and rheumatological and/or hematological manifestations. Patients with VEXAS are typically male aged > 60, with inflammation, and macrocytic anaemia. On suspicion of cancer or infections patients have frequently been exposed to extensive diagnostic procedures and hospital admissions. In this review, we summarise the current knowledge of VEXAS regarding pathogenesis, symptoms, diagnosis, and treatment.
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