AI Article Synopsis
- Beginning in mid-May 2022, there was a significant increase in human monkeypox cases in various non-endemic countries, with over 17,000 cases reported by mid-July across 82 nations.
- The rise in cases highlights the necessity of risk evaluation for informed decision-making and effective communication to curb the spread of the disease.
- Despite the low attention to orthopoxvirus infections since smallpox was eradicated, there remain many unanswered questions regarding the natural history and ecology of monkeypox, which could inform public health strategies and non-pharmacological interventions.
Article Abstract
Starting from mid-May 2022, cases of human monkeypox started to rise in several non-endemic countries. By mid-July, more than 17000 confirmed/suspect cases have been reported by at least 82 countries worldwide, with a regular incremental trend. In order to contain the disease diffusion, risk evaluation is crucial to undertake informed decisions and effective communication campaigns. However, since orthopoxvirus infections so far have attracted low attention, due to the eradication of smallpox 40 years ago, and to the confinement of human monkeypox almost exclusively to endemic areas, several unresolved issues concerning natural history, ecology and pathogenesis remain. To this respect, we identified some open questions and reviewed the relevant literature on monkeypoxvirus and/or related orthopoxviruses. The results will be discussed in the perspective of their relevance to public health decisions, particularly those related to non-pharmacological interventions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530127 | PMC |
| http://dx.doi.org/10.3389/fcimb.2022.1005955 | DOI Listing |
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