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A Framework for Developing an Integrated Shelter Health Model in a Mid-Sized Community: The Windsor Shelter Health Experience.
Healthc Q
October 2024
Jennifer N. Bondy, is a family physician practising in Windsor, ON, and the medical director of WSH and serves as one of the co-chairs on its steering committee. Jennifer is the founder of the WSH research team and is passionate about improving the quality of care for people experiencing homelessness by using evidence-informed decision making to help guide programming.
Windsor Shelter Health is an integrated program that offers comprehensive on-site medical services at shelters and drop-in centres for people experiencing homelessness in Windsor, ON. Although homelessness exists in most Canadian communities, there is more understanding of homelessness responses in larger urban centres. Windsor is a mid-sized border city in southwestern Ontario.
View Article and Find Full Text PDFEnriched environment rescues bisphenol A induced anxiety-like behavior and cognitive impairment by modulating synaptic plasticity.
Ecotoxicol Environ Saf
December 2024
Neuroscience Laboratory for Cognitive and Developmental Disorders, Department of Anatomy, Medical College of Jinan University, Guangzhou, Guangdong 510630, China. Electronic address:
Article Synopsis
- Bisphenol A (BPA) is an endocrine disruptor that negatively impacts the nervous system, leading to anxiety-like behavior and cognitive impairments in mice.
- This study investigates whether an enriched environment (EE) can counteract these effects by enhancing cognitive behavior and reducing anxiety in mice exposed to BPA.
- Results showed that EE treatment improves dendritic spine development, restores excitatory synaptic transmission, and alleviates behavioral issues associated with BPA exposure, highlighting the neuroprotective role of EE.
Associations between life-course FEV/FVC trajectories and respiratory symptoms up to middle age: analysis of data from two prospective cohort studies.
Lancet Respir Med
November 2024
Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia; Murdoch Childrens Research Institute, Parkville, VIC, Australia. Electronic address:
Background: Life-course lung function trajectories leading to airflow obstruction, as measured by impaired FEV/FVC (forced vital capacity), precede the onset of chronic obstructive pulmonary disease (COPD). We aimed to investigate whether individuals on impaired FEV/FVC trajectories have an increased burden of respiratory symptoms, including those who do not meet the spirometric criteria for COPD.
Methods: We analysed serial life-course data from two population-based cohort studies separately, which included respiratory symptoms and spirometry: the Tasmanian Longitudinal Health Study (TAHS, Australia) cohort was recruited at age 6-7 years and followed up until middle age (mean age 53 years; range 51-55); and the Coronary Artery Risk Development in Young Adults (CARDIA, USA) cohort was recruited at a mean age of 25 years (range 18-30) and followed up to a mean age of 55 years (range 47-64).
Home-making or home harms: Perceived and experienced tensions between domestic materiality and ageing.
J Aging Stud
December 2024
NIHR Policy Research Unit in Health and Social Care Workforce, The Policy Institute, King's College London, Virginia Woolf Building, 22 Kingsway, London WC2B 6LE, UK. Electronic address:
Home, as a physical place and psychological construct, is often thought of as being an important locus of ontological security across the life course. However, there is a growing awareness of a darker side to the home (see Gurney, 2021), and home-unmaking practices (see Baxter and Brickell, 2014) that challenge the assumptions of home being purely a place of shelter, comfort, and control and instead foreground the temporal, material, and spatial fluidity of the home, and tensions between privacy and the ability to engage in health-harming behaviours largely unnoticed. Here, a material gerontological approach enables a rethinking of how home, and the household objects contained within, can both promote and undermine well-being as we age.
View Article and Find Full Text PDFLeptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma.
J Allergy Clin Immunol
November 2024
Department of Medicine, Duke University Medical Center, Durham, NC.
Background: Airway tissue eosinophilia can be an observed feature of obesity-associated type 2 (T2) asthma, but the processes mediating this inflammation are unknown.
Objective: To investigate a process whereby leptin, an adipokine elevated in obesity, potentiates pulmonary eosinophilia and eotaxin production by airway fibroblasts in T2 asthma.
Methods: We assessed associations between body mass index and airway eosinophilia as well as leptin and eotaxin production in 78 participants with asthma, 36 of whom exhibited obesity.
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